Gene Symbol | ABCA1 |
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Entrez Gene | 19 |
Alt Symbol | ABC-1, ABC1, CERP, HDLDT1, TGD |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family A (ABC1), member 1 |
Other Description | ATP-binding cassette sub-family A member 1|ATP-binding cassette transporter A1|cholesterol efflux regulatory protein|membrane-bound |
Swissprots | Q96S56 O95477 Q9NQV4 Q9UN06 Q9UN08 Q9UN07 Q5VX33 Q96T85 Q9UN09 |
Accessions | AAD49851 AAD49852 AAD49853 AAD49854 AAF86276 AAK43526 CAC21428 CCQ43324 EAW58992 EAW58993 EAW58994 O95477 AB037924 BAB07875 AB055982 BAB63210 AB208839 BAD92076 AB445477 BAH10664 AF165281 AAD49849 AF258627 AAF69513 AF285167 AAF98175 AJ012376 CAA10005 AK024328 AK027864 BC034824 BC146856 AAI46857 BU753834 BX955241 XM_005251773 XP_005251830 XM_005251776 XP_005251833 XM_011518339 XP_011516641 XM_011518340 XP_011516642 XM_011518341 XP_011516643 XM_011518342 XP_011516644 XM_011518343 XP_011516645 XM_011518344 XP_011516646 NM_005502 NP_005493 |
Function | cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport. |
Subcellular Location | Membrane {ECO:0000269|PubMed:19258317, ECO:0000269|PubMed:19556522}; Multi-pass membrane protein {ECO:0000269|PubMed:19258317, ECO:0000269|PubMed:19556522}. |
Tissue Specificity | Widely expressed, but most abundant in macrophages. |
Top Pathways | ABC transporters, Fat digestion and absorption |
ABCA1 peptide - ab14148 from Abcam
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Human ABCA1 protein fragment - ab125995 from Abcam
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ABCA1 Antibody Blocking Peptide - LS-E16060 from LifeSpan Bioscience
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ABCA1 Antibody Blocking Peptide - LS-E31283 from LifeSpan Bioscience
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ABCA1 Blocking Peptide - NB400-105PEP from Novus Biologicals
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Recombinant Human ABCA1 Protein - H00000019-Q01 from Novus Biologicals
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Abca1 Blocking Peptide - 33R-6863 from Fitzgerald
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ABCA1 Blocking Peptide - abx064120 from Abbexa
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ABCA1 - H00000019-Q01-10 from Acris Antibodies
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ABCA1 - H00000019-Q01-25 from Acris Antibodies
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ABCA1 fusion protein - ag14939 from Proteintech Group
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Recombinant Human ABCA1 - ABCA1-459H from Creative Biomart
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Recombinant ATP Binding Cassette Transporter A1 (ABCA1) - RPB242Hu01 from Uscn Life Science Inc.
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Recombinant ATP Binding Cassette Transporter A1 (ABCA1) - RPB242Mu01 from Uscn Life Science Inc.
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Recombinant ATP Binding Cassette Transporter A1 (ABCA1) - RPB242Mu02 from Uscn Life Science Inc.
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ABCA1 Blocking Peptide - CBP2926 from Cohesion Biosciences
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Recombinant ATP Binding Cassette Transporter A1 (ABCA1) - RPB242Hu01 from Cloud-clone
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Recombinant Human TAFA-2 (Carrier-free) - 21-7133 from Tonbo Biosciences
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ATP-binding cassette sub-family A member 1 (ABCA1), partial, Recombinant Protein - MBS1176942 from MyBioSource
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ABCA1 Peptide, Human - M34GP00028H from Creative Peptides
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ABCA1 fusion protein - Ag25854 from Proteintech Group
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ABCA1 Recombinant Protein (OPCD01001) - OPCD01001 from Aviva Systems Biology
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ABCA1 Recombinant Protein Antigen - NBP2-58550PEP from Novus Biologicals
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ABCA1 fusion protein - Ag24118 from Proteintech Group
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Recombinant Human ABCA1 protein, GST-tagged - ABCA1-178H from Creative Biomart
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