| Gene Symbol |
ERLEC1
|
| Entrez Gene |
27248
|
| Alt Symbol |
C2orf30, CIM, CL24936, CL25084, HEL117, XTP3-B, XTP3TPB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
endoplasmic reticulum lectin 1
|
| Other Description |
ER lectin|XTP3-transactivated gene B protein|XTP3-transactivated protein B|cancer invasion and metastasis-related|epididymis luminal protein 117|erlectin 1
|
| Swissprots |
Q96DZ1 Q9UQL4 Q6UWN7 B5MC72 B2RDB4 O95901 Q9NUY7
|
| Accessions |
AAY24352 EAX00163 EAX00164 EAX00165 EAX00166 Q96DZ1 AA687108 AF131743 AAD20029 AF131849 AAD20060 AK001913 BAA91974 AK315477 BAG37861 AY358717 AAQ89079 AY453410 AAR26725 BC013129 AAH13129 BC022228 AAH22228 BQ017438 BU784879 DB451941 DB539199 DQ894762 ABM85688 EU794676 ACJ13730 XM_011532766 XP_011531068 NM_001127397 NP_001120869 NM_001127398 NP_001120870 NM_015701 NP_056516
|
| Function |
Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins. {ECO:0000269|PubMed:16531414, ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18502753}.
|
| Subcellular Location |
Endoplasmic reticulum lumen {ECO:0000269|PubMed:16531414, ECO:0000269|PubMed:18502753}.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|
![Western Blot: ERLEC1 Overexpression Lysate (Adult Normal) [NBL1-08410] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ERLEC1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7236_ERLEC1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08410-img0002.jpg)