Gene Symbol | ERLEC1 |
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Entrez Gene | 27248 |
Alt Symbol | C2orf30, CIM, CL24936, CL25084, HEL117, XTP3-B, XTP3TPB |
Species | Human |
Gene Type | protein-coding |
Description | endoplasmic reticulum lectin 1 |
Other Description | ER lectin|XTP3-transactivated gene B protein|XTP3-transactivated protein B|cancer invasion and metastasis-related|epididymis luminal protein 117|erlectin 1 |
Swissprots | Q96DZ1 Q9UQL4 Q6UWN7 B5MC72 B2RDB4 O95901 Q9NUY7 |
Accessions | AAY24352 EAX00163 EAX00164 EAX00165 EAX00166 Q96DZ1 AA687108 AF131743 AAD20029 AF131849 AAD20060 AK001913 BAA91974 AK315477 BAG37861 AY358717 AAQ89079 AY453410 AAR26725 BC013129 AAH13129 BC022228 AAH22228 BQ017438 BU784879 DB451941 DB539199 DQ894762 ABM85688 EU794676 ACJ13730 XM_011532766 XP_011531068 NM_001127397 NP_001120869 NM_001127398 NP_001120870 NM_015701 NP_056516 |
Function | Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins. {ECO:0000269|PubMed:16531414, ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18502753}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000269|PubMed:16531414, ECO:0000269|PubMed:18502753}. |
Top Pathways | Protein processing in endoplasmic reticulum |
XTP3-B (C-14) - sc-161408 from Santa Cruz Biotechnology
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XTP3-B (N-17) - sc-161409 from Santa Cruz Biotechnology
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Anti-ERLEC1 antibody - ab102046 from Abcam
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Anti-ERLEC1 antibody [EPR13849] - ab181166 from Abcam
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Anti-ERLEC1 Antibody (aa359-408) - LS-C116609 from LifeSpan Bioscience
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ERLEC1 Antibody - NBP1-86802 from Novus Biologicals
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ERLEC1 Antibody - NBP1-86803 from Novus Biologicals
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ERLEC1 Antibody - NBP1-86801 from Novus Biologicals
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Monoclonal Anti-XTP3-B antibody produced in mouse - SAB4200339 from Sigma-Aldrich
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Anti-XTP3-B antibody produced in rabbit - SAB4200062 from Sigma-Aldrich
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Anti-ERLEC1 antibody produced in rabbit - HPA031501 from Sigma-Aldrich
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Anti-ERLEC1 antibody produced in rabbit - HPA031503 from Sigma-Aldrich
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Anti-ERLEC1 antibody produced in rabbit - HPA031502 from Sigma-Aldrich
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C2orf30 antibody - middle region (ARP55331_P050) - ARP55331_P050 from Aviva Systems Biology
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C2orf30 antibody, Internal - GTX45297 from GeneTex
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C2orf30 antibody - 70R-4009 from Fitzgerald
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ERLEC1 antibody (FITC) - orb187739 from Biorbyt
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ERLEC1 antibody - H00027248-B01P from Acris Antibodies
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C2orf30 Antibody - GWB-MT793A from Genway Biotech
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Anti-ERLEC1 monoclonal antibody, clone FQS24950 - DCABH-7144 from Creative Diagnostics
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C2orf30, Polyclonal Antibody - MBS839780 from MyBioSource
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Anti-C2orf30 (XTP3-B) (361-375) antibody produced in rabbit - SAB1101331 from Sigma-Aldrich
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ERLEC1 antibody - TA333792 from Acris Antibodies
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Anti-ERLEC1 polyclonal antibody - CABT-BL4597 from Creative Diagnostics
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ERLEC1 antibody - orb183426 from Biorbyt
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