ERLEC1

Gene Symbol ERLEC1
Entrez Gene 27248
Alt Symbol C2orf30, CIM, CL24936, CL25084, HEL117, XTP3-B, XTP3TPB
Species Human
Gene Type protein-coding
Description endoplasmic reticulum lectin 1
Other Description ER lectin|XTP3-transactivated gene B protein|XTP3-transactivated protein B|cancer invasion and metastasis-related|epididymis luminal protein 117|erlectin 1
Swissprots Q96DZ1 Q9UQL4 Q6UWN7 B5MC72 B2RDB4 O95901 Q9NUY7
Accessions AAY24352 EAX00163 EAX00164 EAX00165 EAX00166 Q96DZ1 AA687108 AF131743 AAD20029 AF131849 AAD20060 AK001913 BAA91974 AK315477 BAG37861 AY358717 AAQ89079 AY453410 AAR26725 BC013129 AAH13129 BC022228 AAH22228 BQ017438 BU784879 DB451941 DB539199 DQ894762 ABM85688 EU794676 ACJ13730 XM_011532766 XP_011531068 NM_001127397 NP_001120869 NM_001127398 NP_001120870 NM_015701 NP_056516
Function Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins. {ECO:0000269|PubMed:16531414, ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18502753}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:16531414, ECO:0000269|PubMed:18502753}.
Top Pathways Protein processing in endoplasmic reticulum

XTP3-B (C-14) - sc-161408 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
XTP3-B (C-14): sc-161408. Western blot analysis of XTP3-B expression in HL-60 whole cell lysate.

XTP3-B (N-17) - sc-161409 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
XTP3-B (N-17): sc-161409. Western blot analysis of XTP3-B expression in IMR-32 (A), HL-60 (B), JAR (C) and Hep G2 (D) whole cell lysates.

Anti-ERLEC1 antibody - ab102046 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ERLEC1 antibody (ab102046) at 1 µg/ml + THP1 cell lysate at 10 µg

Anti-ERLEC1 antibody [EPR13849] - ab181166 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13849
Anti-ERLEC1 antibody [EPR13849] (ab181166) at 1/10000 dilution + HepG2 lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-ERLEC1 Antibody (aa359-408) - LS-C116609 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ERLEC1 / C2orf30 antibody LS-C116609 Western blot of THP-1 cell lysate.

ERLEC1 Antibody - NBP1-86802 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ERLEC1 Antibody [NBP1-86802] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp

ERLEC1 Antibody - NBP1-86803 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ERLEC1 Antibody [NBP1-86803] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

ERLEC1 Antibody - NBP1-86801 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: ERLEC1 Antibody [NBP1-86801] - Staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells.

Monoclonal Anti-XTP3-B antibody produced in mouse - SAB4200339 from Sigma-Aldrich

Prices $342.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone XTP3-10
<B>Immunoblotting</B><BR/>Whole extract of HEK-293T cells overexpressing human XTP3-B was separated on SDS-PAGE and probed with Monoclonal Anti-XTP3-B Clone: XTP3-10 (<B>Cat. No. SAB4200339</B>). The antibody was developed using Goat Anti-Mouse IgG-Peroxidase (<B>Cat. No. A2304</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. 2 μg/mL antibody<BR/>2. 5 μg/mL antibody<BR/>3. 5 μg/mL antibody + XTP3-B immunizing peptide

Anti-XTP3-B antibody produced in rabbit - SAB4200062 from Sigma-Aldrich

Prices $61.10, $354.00
Sizes 25 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>NRK cells were fixed and permeabilized with cold methanol followed by cold acetone. Fixed cells were stained with 5 μg/mL Rabbit Anti-XTP3-B (<B>Cat. No. SAB4200062</B>). The antibody was developed using Goat Anti-Rabbit IgG, Atto 488 conjugate (<B>Cat. No.18772</B>).

Anti-ERLEC1 antibody produced in rabbit - HPA031501 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ERLEC1: <B>Cat. No. HPA031501</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.

Anti-ERLEC1 antibody produced in rabbit - HPA031503 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ERLEC1: <B>Cat. No. HPA031503</B>: Immunohistochemical staining of human cerebellum shows strong nuclear/nucleolar and cytoplasmic positivity in Purkinje cells.

Anti-ERLEC1 antibody produced in rabbit - HPA031502 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ERLEC1: <B>Cat. No. HPA031502</B>: Immunohistochemical staining of human cerebral cortex shows cytoplasmic positivity in neuronal cells.

C2orf30 antibody - middle region (ARP55331_P050) - ARP55331_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C2orf30 antibody, Internal - GTX45297 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-C2orf30 antibody, Internal used in Western blot. GTX45297

C2orf30 antibody - 70R-4009 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

ERLEC1 antibody (FITC) - orb187739 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

ERLEC1 antibody - H00027248-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

C2orf30 Antibody - GWB-MT793A from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ERLEC1 monoclonal antibody, clone FQS24950 - DCABH-7144 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal
Clone FQS24950

C2orf30, Polyclonal Antibody - MBS839780 from MyBioSource

Prices $455.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-C2orf30 (XTP3-B) (361-375) antibody produced in rabbit - SAB1101331 from Sigma-Aldrich

Prices $338.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti- C2orf30 (XTP3-B) (361-375) (RB): <B>Cat. No. SAB1101331</B>: Immunofluorescence of HUVEC cells using Anti-C2orf30 (XTP3-B) (361-375) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

ERLEC1 antibody - TA333792 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
WB Suggested Anti-C2orf30 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: THP-1 cell lysate

Anti-ERLEC1 polyclonal antibody - CABT-BL4597 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

ERLEC1 antibody - orb183426 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
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