Gene Symbol | ERLEC1 |
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Entrez Gene | 27248 |
Alt Symbol | C2orf30, CIM, CL24936, CL25084, HEL117, XTP3-B, XTP3TPB |
Species | Human |
Gene Type | protein-coding |
Description | endoplasmic reticulum lectin 1 |
Other Description | ER lectin|XTP3-transactivated gene B protein|XTP3-transactivated protein B|cancer invasion and metastasis-related|epididymis luminal protein 117|erlectin 1 |
Swissprots | Q96DZ1 Q9UQL4 Q6UWN7 B5MC72 B2RDB4 O95901 Q9NUY7 |
Accessions | AAY24352 EAX00163 EAX00164 EAX00165 EAX00166 Q96DZ1 AA687108 AF131743 AAD20029 AF131849 AAD20060 AK001913 BAA91974 AK315477 BAG37861 AY358717 AAQ89079 AY453410 AAR26725 BC013129 AAH13129 BC022228 AAH22228 BQ017438 BU784879 DB451941 DB539199 DQ894762 ABM85688 EU794676 ACJ13730 XM_011532766 XP_011531068 NM_001127397 NP_001120869 NM_001127398 NP_001120870 NM_015701 NP_056516 |
Function | Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins. {ECO:0000269|PubMed:16531414, ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18502753}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000269|PubMed:16531414, ECO:0000269|PubMed:18502753}. |
Top Pathways | Protein processing in endoplasmic reticulum |
XTP3-B CRISPR/Cas9 KO Plasmid (h) - sc-406470 from Santa Cruz Biotechnology
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XTP3-B HDR Plasmid (h) - sc-406470-HDR from Santa Cruz Biotechnology
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XTP3-B Double Nickase Plasmid (h) - sc-406470-NIC from Santa Cruz Biotechnology
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XTP3-B Double Nickase Plasmid (h2) - sc-406470-NIC-2 from Santa Cruz Biotechnology
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XTP3-B CRISPR Activation Plasmid (h) - sc-406470-ACT from Santa Cruz Biotechnology
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XTP3-B CRISPR Activation Plasmid (h2) - sc-406470-ACT-2 from Santa Cruz Biotechnology
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XTP3-B Lentiviral Activation Particles (h) - sc-406470-LAC from Santa Cruz Biotechnology
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XTP3-B Lentiviral Activation Particles (h2) - sc-406470-LAC-2 from Santa Cruz Biotechnology
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XTP3-B siRNA (h) - sc-94979 from Santa Cruz Biotechnology
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XTP3-B shRNA Plasmid (h) - sc-94979-SH from Santa Cruz Biotechnology
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XTP3-B shRNA (h) Lentiviral Particles - sc-94979-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU119151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7967 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7967 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06699 from Sigma-Aldrich
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ERLEC1 siRNA (Human) - CRH9041 from Cohesion Biosciences
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ERLEC1 - MBS8209994 from MyBioSource
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shRNA set against Human ERLEC1 (NM_015701.4) - SHH287109 from Creative biogene
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ERLEC1 shRNA Plasmid (Human) - CHH9041 from Cohesion Biosciences
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ERLEC1 miRNA 3'UTR clone - MiUTR3H-11731 from Creative biogene
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ERLEC1 miRNA 3'UTR clone - MiUTR3H-11732 from Creative biogene
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ERLEC1 miRNA 3'UTR clone - MiUTR3H-11733 from Creative biogene
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