MBOAT2

Gene Symbol MBOAT2
Entrez Gene 129642
Alt Symbol LPCAT4, OACT2
Species Human
Gene Type protein-coding
Description membrane bound O-acyltransferase domain containing 2
Other Description 1-acylglycerophosphate O-acyltransferase|1-acylglycerophosphoethanolamine O-acyltransferase|LPAAT|LPEAT|LPLAT 2|O-acyltransferase (membrane bound) domain containing 2|O-acyltransferase domain-containing protein 2|lyso-PA acyltransferase|lyso-PE acyltransferase|lysophosphatidic acid acyltransferase|lysophosphatidylethanolamine acyltransferase|lysophospholipid acyltransferase 2|membrane-bound O-acyltransferase domain-containing protein 2
Swissprots Q8NCE7 Q96KY4 Q6ZWT7 A9EDR2
Accessions EAX01013 Q6ZWT7 AB305044 BAF93900 AF052107 AK027321 BAC85105 AK074779 BAC11204 AK295907 BAH12219 AK309818 AK315881 BAF98772 BC016005 AAH16005 BC146871 AAI46872 BC157827 AAI57828 XM_011510309 XP_011508611 XM_011510310 XP_011508612 XM_011510311 XP_011508613 XM_011510312 XP_011508614 XM_011510313 XP_011508615 XM_011510314 XP_011508616 XR_241248 NM_138799 NP_620154
Function Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3- phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2- diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. {ECO:0000269|PubMed:18772128}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in neutrophils. {ECO:0000269|PubMed:18772128}.
Top Pathways Glycerolipid metabolism, Glycerophospholipid metabolism

Panoply™ Human MBOAT2 Knockdown Stable Cell Line - CSC-DC009287 from Creative biogene

Category Cell Line
Species Human
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