Gene Symbol | TNFRSF17 |
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Entrez Gene | 608 |
Alt Symbol | BCM, BCMA, CD269, TNFRSF13A |
Species | Human |
Gene Type | protein-coding |
Description | tumor necrosis factor receptor superfamily, member 17 |
Other Description | B cell maturation antigen|B-cell maturation factor|B-cell maturation protein|tumor necrosis factor receptor superfamily member 17 |
Swissprots | Q02223 Q2TQ40 |
Accessions | AAB67251 AAR84240 BAB60895 CAA82690 CAJ90608 CAJ90610 EAW85129 Q02223 AY684975 AAV92616 BC058291 AAH58291 EF152353 ABN42508 EF152354 ABN42509 EF152355 ABN42510 EF152356 ABN42511 Z14954 CAA78679 Z29575 CAA82691 NM_001192 NP_001183 |
Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}. |
Subcellular Location | Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures. |
Tissue Specificity | Expressed in mature B-cells, but not in T- cells or monocytes. |
Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production |
Active human BCMA protein fragment - ab184887 from Abcam
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BCMA peptide - ab6087 from Abcam
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Human BCMA full length protein - ab132007 from Abcam
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Human BCMA full length protein - ab192125 from Abcam
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Human BCMA protein fragment - ab139210 from Abcam
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Human BCMA protein fragment - ab111458 from Abcam
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Human BCMA protein fragment - ab50089 from Abcam
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Mouse BCMA protein fragment - ab109162 from Abcam
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TNFRSF17 / BCMA Antibody Blocking Peptide - LS-E4021 from LifeSpan Bioscience
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TNFRSF17 / BCMA Antibody Blocking Peptide - LS-E23313 from LifeSpan Bioscience
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TNFRSF17 / BCMA Antibody Blocking Peptide - LS-E29957 from LifeSpan Bioscience
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Recombinant Human BCMA/TNFRSF17 Protein - NBP2-34903 from Novus Biologicals
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BCMA/TNFRSF17 Recombinant Protein - H00000608-P01 from Novus Biologicals
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Recombinant Human BCMA/TNFRSF17 Protein - NBP2-22905 from Novus Biologicals
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BCMA/TNFRSF17 Recombinant Protein - P3590 from Novus Biologicals
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BCMA/TNFRSF17 Blocking Peptide - NBP1-76774PEP from Novus Biologicals
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BCMA/TNFRSF17 Protein - NBP1-99861 from Novus Biologicals
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BCMA/TNFRSF17 Recombinant Protein - H00000608-G01 from Novus Biologicals
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TNFRSF17-Antibody-Center-Blocking-Peptide - BP16248c from Abgent, a WuXi AppTec company
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BCMA recombinant protein - GTX65010 from GeneTex
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BCMA Recombinant Protein - GTX48473-PRO from GeneTex
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BCMA Peptide - GTX26087 from GeneTex
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Recombinant Human BCMA/TNFRSF17 Fc Chimera, CF - 193-BC-050 from R&D Systems
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TNFRSF17 Protein (OPPA01665) - OPPA01665 from Aviva Systems Biology
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Cynomolgus TNFRSF17 protein - orb139774 from Biorbyt
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