Gene Symbol | TNFRSF17 |
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Entrez Gene | 608 |
Alt Symbol | BCM, BCMA, CD269, TNFRSF13A |
Species | Human |
Gene Type | protein-coding |
Description | tumor necrosis factor receptor superfamily, member 17 |
Other Description | B cell maturation antigen|B-cell maturation factor|B-cell maturation protein|tumor necrosis factor receptor superfamily member 17 |
Swissprots | Q02223 Q2TQ40 |
Accessions | AAB67251 AAR84240 BAB60895 CAA82690 CAJ90608 CAJ90610 EAW85129 Q02223 AY684975 AAV92616 BC058291 AAH58291 EF152353 ABN42508 EF152354 ABN42509 EF152355 ABN42510 EF152356 ABN42511 Z14954 CAA78679 Z29575 CAA82691 NM_001192 NP_001183 |
Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}. |
Subcellular Location | Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures. |
Tissue Specificity | Expressed in mature B-cells, but not in T- cells or monocytes. |
Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production |
BCMA (D-6) - sc-390147 from Santa Cruz Biotechnology
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BCMA (G-4) - sc-390336 from Santa Cruz Biotechnology
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BCMA (C-19) - sc-11746 from Santa Cruz Biotechnology
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BCMA (N-16) - sc-11743 from Santa Cruz Biotechnology
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BCMA (H-54) - sc-366034 from Santa Cruz Biotechnology
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Anti-BCMA antibody - ab5972 from Abcam
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Anti-BCMA antibody - ab54834 from Abcam
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Anti-BCMA antibody [MM0108-3D44] - ab89152 from Abcam
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Anti-BCMA antibody [Vicky-1] - ab17323 from Abcam
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Anti-BCMA antibody - C-terminal - ab199264 from Abcam
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Anti-TNFRSF17 / BCMA Antibody (clone 1F10) - LS-C196740 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (C-Terminus) IHC-plus⢠- LS-B2728 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (clone Vicky-1, FITC) - LS-C18662 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (clone Vicky-2) - LS-C18716 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (clone Vicky-1) - LS-C53526 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (C-Terminus) - LS-C83463 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (aa62-92, AP) - LS-C241938 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (aa62-92, APC) - LS-C241939 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (aa62-92, Biotin) - LS-C241940 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (aa62-92, FITC) - LS-C241941 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (aa62-92, PE) - LS-C241942 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (aa62-92, Azide-free, HRP) - LS-C247094 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (C-Terminus) - LS-C151578 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (aa71-184, Biotin) - LS-C300285 from LifeSpan Bioscience
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Anti-TNFRSF17 / BCMA Antibody (aa71-184, FITC) - LS-C304695 from LifeSpan Bioscience
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