IFITM3

Gene Symbol IFITM3
Entrez Gene 10410
Alt Symbol 1-8U, DSPA2b, IP15
Species Human
Gene Type protein-coding
Description interferon induced transmembrane protein 3
Other Description dispanin subfamily A member 2b|interferon-induced transmembrane protein 3|interferon-inducible protein 1-8U
Swissprots Q01628 Q96J15 Q96HK8 Q53Y76
Accessions AFF60304 AFF60305 AFF60306 AFF60307 AFF60308 AFF60309 AFF60310 AFF60311 AFF60312 AFF60313 AFF60314 AFF60315 AFF60316 AFF60317 AFF60318 AFF60319 AFF60320 AFF60321 AFF60322 AFF60323 AFF60324 AFF60325 AFF60326 AFF60327 AFF60328 AFF60329 AFF60330 AFF60331 AFF60332 AFF60333 AFF60334 AFF60335 AFF60336 AFF60337 AFF60338 AFF60339 AFF60340 AFF60341 AFF60342 AFF60343 AFF60344 AFF60345 AFF60346 AFF60347 AFF60348 AFF60349 AFF60350 AFF60351 AFF60352 AFF60353 AFF60354 AFF60355 EAW50866 Q01628 AI355192 AK292173 BAF84862 AM392723 CAL37601 AM393694 CAL38570 BC006794 AAH06794 BC008417 AAH08417 BC022439 AAH22439 BC070243 AAH70243 BQ937265 BT006892 AAP35538 DB261103 DQ891098 ABM82024 DQ894280 ABM85206 X57352 CAA40626 NM_021034 NP_066362 NR_049759
Function IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2- mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localizatio
Subcellular Location Cell membrane; Single-pass type II membrane protein. Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein.

IFITM3 CRISPR/Cas9 KO Plasmid (h) - sc-403281 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM3 HDR Plasmid (h) - sc-403281-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM3 Double Nickase Plasmid (h) - sc-403281-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM3 Double Nickase Plasmid (h2) - sc-403281-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM3 CRISPR Activation Plasmid (h) - sc-403281-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM3 CRISPR Activation Plasmid (h2) - sc-403281-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM3 Lentiviral Activation Particles (h) - sc-403281-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM3 Lentiviral Activation Particles (h2) - sc-403281-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFITM3 siRNA (h) - sc-97053 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IFITM3 shRNA Plasmid (h) - sc-97053-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IFITM3 shRNA (h) Lentiviral Particles - sc-97053-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IFITM3/Fragilis RNAi - H00010410-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU058291 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU222801 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10472 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10472 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00720 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00720

IFITM3 siRNA (Human) - CRH7058 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IFITM3 - MBS8208387 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IFITM3 (NM_021034.2) - SHH316973 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human IFITM3(NM_021034.2) - SHL166212 from Creative biogene

Category siRNA
Species Reactivities Human

Human IFITM3 siRNA - orb267560 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IFITM3 shRNA Plasmid (Human) - CHH7058 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IFITM3 miRNA 3'UTR clone - MiUTR1H-04808 from Creative biogene

Species Reactivities Human
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