SPPL3

Gene Symbol	SPPL3
Entrez Gene	121665
Alt Symbol	IMP2, MDHV1887, PRO4332, PSH1, PSL4
Species	Human
Gene Type	protein-coding
Description	signal peptide peptidase like 3
Other Description	SPP-like 3|intramembrane protease 2|presenilin homologous protein 1|presenilin-like protein 4|signal peptide peptidase-like 3
Swissprots	Q3MJ04 Q96DD9 Q8TCT6 Q8TAU4
Accessions	CCQ43833 EAW98220 EAW98221 EAW98222 EAW98223 Q8TCT6 AB252457 BAF30928 AF086117 AI676074 AJ345030 CAC87791 AJ420898 CAD13135 AK074916 BAC11290 AK097149 AK223590 BAD97310 AK291161 BAF83850 AL110147 CAB53661 AY169313 AAO12538 AY358767 AAQ89127 BC009551 AAH09551 BC025781 AAH25781 BC073910 AAH73910 BC101625 AAI01626 BC101627 AAI01628 BU932077 XM_011537924 XP_011536226 XM_011537925 XP_011536227 NM_139015 NP_620584
Function	Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. {ECO:0000269|PubMed:16873890}.
Subcellular Location	Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Restricted to the early secretory compartment.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:15385547}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UNQ1887 full length protein - ab165177 from Abcam Category Protein Source Wheat germ Species Human

Human UNQ1887 protein fragment - ab165178 from Abcam Category Protein Source Wheat germ Species Human

SPPL3 / IMP2 Antibody Blocking Peptide - LS-E8202 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPPL3 / IMP2 Antibody Blocking Peptide - LS-E18964 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SPPL3 Protein - H00121665-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SPPL3 Protein - H00121665-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SPPL3 Peptide - P1941 from Novus Biologicals Category Peptide Species Human

SPPL3-Antibody-N-term-Blocking-Peptide - BP6313a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UNQ1887 Blocking Peptide - 33R-9700 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPPL3 - H00121665-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SPPL3 - H00121665-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SPPL3 - H00121665-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SPPL3 - H00121665-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

UNQ1887 fusion protein - ag11747 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

UNQ1887 fusion protein - ag11826 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SPPL3 Protein - NBP2-32505PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SPPL3-Antibody-C-term-Blocking-Peptide - BP6313b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPPL3 Peptide, Human - M34GP15087H from Creative Peptides Category Peptide Source Synthetic. Species Human

SPPL3 Recombinant Protein Antigen - NBP2-55109PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Signal peptide peptidase-like 3 (SPPL3), Recombinant Protein - MBS7096308 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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