SPPL3

Gene Symbol SPPL3
Entrez Gene 121665
Alt Symbol IMP2, MDHV1887, PRO4332, PSH1, PSL4
Species Human
Gene Type protein-coding
Description signal peptide peptidase like 3
Other Description SPP-like 3|intramembrane protease 2|presenilin homologous protein 1|presenilin-like protein 4|signal peptide peptidase-like 3
Swissprots Q3MJ04 Q96DD9 Q8TCT6 Q8TAU4
Accessions CCQ43833 EAW98220 EAW98221 EAW98222 EAW98223 Q8TCT6 AB252457 BAF30928 AF086117 AI676074 AJ345030 CAC87791 AJ420898 CAD13135 AK074916 BAC11290 AK097149 AK223590 BAD97310 AK291161 BAF83850 AL110147 CAB53661 AY169313 AAO12538 AY358767 AAQ89127 BC009551 AAH09551 BC025781 AAH25781 BC073910 AAH73910 BC101625 AAI01626 BC101627 AAI01628 BU932077 XM_011537924 XP_011536226 XM_011537925 XP_011536227 NM_139015 NP_620584
Function Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. {ECO:0000269|PubMed:16873890}.
Subcellular Location Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Restricted to the early secretory compartment.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:15385547}.

SPPL3 (Q-12) - sc-161228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SPPL3 (T-13) - sc-161229 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SPPL3 antibody - N-terminal - ab175586 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SPPL3 antibody - N-terminal (ab175586) at 1/1000 dilutionLane 1 : 293 cell lysates, nontransfectedLane 2 : 293 cell lysates, transiently transfected with the UNQ1887 geneLysates/proteins at 2 µg per lane.

Anti-UNQ1887 antibody - ab194573 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-UNQ1887 antibody (ab194573) at 1/500 dilution + Human ovarian cancer tissue lysate at 50 µg

Anti-UNQ1887 antibody - ab105863 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-UNQ1887 antibody (ab105863) at 1 µg/ml + A549 cell lysate at 10 µg

Anti-SPPL3 / IMP2 Antibody (N-Terminus, AP) - LS-C245960 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPPL3 / IMP2 Antibody (N-Terminus, APC) - LS-C245961 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPPL3 / IMP2 Antibody (N-Terminus, Biotin) - LS-C245962 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPPL3 / IMP2 Antibody (N-Terminus, PE) - LS-C245965 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPPL3 / IMP2 Antibody (N-Terminus, Azide-free, HRP) - LS-C247886 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPPL3 / IMP2 Antibody (N-Terminus) - LS-C330674 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPPL3 / IMP2 Antibody (aa50-81) - LS-C100062 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of SPPL3(arrow) using rabbit polyclonal SPPL3 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPPL3 gene (Lane 2) (Origene Technologies).

Anti-SPPL3 / IMP2 Antibody (aa215-264) - LS-C116507 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SPPL3 / IMP-2 antibody LS-C116507 Western blot of A549 cell lysate.

Anti-SPPL3 / IMP2 Antibody (N-Terminus, FITC) - LS-C245963 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

SPPL3 Antibody - NBP2-32505 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SPPL3 Antibody [NBP2-32505] - liver

SPPL3 Antibody - NBP1-57070 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SPPL3 Antibody [NBP1-57070] - A549 cell lysate, concentration 0.2-1 ug/ml.

SPPL3 Antibody - H00121665-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
SPPL3 polyclonal antibody (A01), Lot # 060516JCS1. Western Blot analysis of SPPL3 expression in human ovary cancer.

Anti-SPPL3 antibody produced in rabbit - HPA059958 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SPPL3: <B>Cat. No. HPA059958</B>: Immunohistochemical staining of Human testis shows strong cytoplasmic positivity in subset of cells in seminiferous ducts.

Anti-SPPL3 (C-term) antibody produced in rabbit - SAB1300768 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPPL3 (N-term) antibody produced in rabbit - SAB1300767 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SPPL3 (N-term) Antibody: <B>Cat. No. SAB1300767</B>: SPPL3 in HEK 293 cell line lysates either non-transfected (Lane 1) or transiently transfected (Lane 2) with Anti-SPPL3 (N-term) Antibody at 4.0 μg/mL.

UNQ1887 antibody - middle region (ARP52668_P050) - ARP52668_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SPPL3-Antibody-N-term - AP6313a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of SPPL3(arrow) using rabbit polyclonal SPPL3 Antibody (N-term) (Cat.#AP6313a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPPL3 gene (Lane 2) (Origene Technologies).

SPPL3 Antibody - N-terminal region (OAAB16633) - OAAB16633 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

UNQ1887 antibody - 70R-4578 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

SPPL3 Antibody - abx032796 from Abbexa

Host Rabbit
Clonality Polyclonal
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