CACNB1

Gene Symbol	CACNB1
Entrez Gene	782
Alt Symbol	CAB1, CACNLB1, CCHLB1
Species	Human
Gene Type	protein-coding
Description	calcium channel, voltage-dependent, beta 1 subunit
Other Description	calcium channel voltage-dependent subunit beta 1|calcium channel, L type, beta 1 polypeptide|dihydropyridine-sensitive L-type, calcium channel beta-1 subunit|voltage-dependent L-type calcium channel subunit beta-1
Swissprots	Q8N3X9 Q9UD79 Q02641 Q9C085 Q02640 Q02639 O15331 A8K114
Accessions	AAB58779 AAB58780 AAB58781 CAA79824 CAA79825 EAW60556 EAW60557 EAW60558 EAW60559 EAW60560 EAW60561 EAW60562 EAW60563 EAW60564 Q02641 AA694045 AB054985 BAB21444 AB209176 BAD92413 AK127283 BAG54473 AK289729 BAF82418 AK297643 BAH12640 AK300666 BAH13323 AK312385 AY393857 AAQ97605 BC037311 AAH37311 BP217857 DQ891688 ABM82614 EU176608 ABW03409 L06110 AAA36167 L06111 AAA36168 L06112 AAA36169 M76560 AAA51894 M92301 AAA35631 M92302 AAA35632 M92303 AAA35633 XM_005257645 XP_005257702 XM_005257646 XP_005257703 XM_005257647 XP_005257704 XM_006722072 XP_006722135 XM_011525186 XP_011523488 NM_000723 NP_000714 NM_199247 NP_954855 NM_199248 NP_954856
Function	The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Subcellular Location	Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity	Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle. {ECO:0000269|PubMed:8107964}.
Top Pathways	MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CACNB1 293T Cell Transient Overexpression Lysate(Denatured) - H00000782-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CACNB1 overexpression lysate - LY403703 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

CACNB1 overexpression lysate - LY404593 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

CACNB1 overexpression lysate - LY424552 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CACNB1 293 Cell Lysate - 403189 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

CACNB1 Overexpression Lysate (Denatured) - H00000782-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

CACNB1 Overexpression Lysate (Native) - NBL1-08628 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

L-type Ca ++ CP β1 (h): 293T Lysate - sc-176607 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CACNB1 Over-expression Lysate Product - GWB-668ADD from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Panoply™ Human CACNB1 Knockdown Stable Cell Line - CSC-DC002266 from Creative biogene Category Cell Line Species Human

CACNB1 Knockout Cell Line-HeLa - CSC-RT1924 from Creative biogene Category Cell Line Species Human

CACNB1 KO Cell Lysate-HeLa - CLKO-1780 from Creative biogene Category Cell Lysate

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