CACNB1

Gene Symbol	CACNB1
Entrez Gene	782
Alt Symbol	CAB1, CACNLB1, CCHLB1
Species	Human
Gene Type	protein-coding
Description	calcium channel, voltage-dependent, beta 1 subunit
Other Description	calcium channel voltage-dependent subunit beta 1|calcium channel, L type, beta 1 polypeptide|dihydropyridine-sensitive L-type, calcium channel beta-1 subunit|voltage-dependent L-type calcium channel subunit beta-1
Swissprots	Q8N3X9 Q9UD79 Q02641 Q9C085 Q02640 Q02639 O15331 A8K114
Accessions	AAB58779 AAB58780 AAB58781 CAA79824 CAA79825 EAW60556 EAW60557 EAW60558 EAW60559 EAW60560 EAW60561 EAW60562 EAW60563 EAW60564 Q02641 AA694045 AB054985 BAB21444 AB209176 BAD92413 AK127283 BAG54473 AK289729 BAF82418 AK297643 BAH12640 AK300666 BAH13323 AK312385 AY393857 AAQ97605 BC037311 AAH37311 BP217857 DQ891688 ABM82614 EU176608 ABW03409 L06110 AAA36167 L06111 AAA36168 L06112 AAA36169 M76560 AAA51894 M92301 AAA35631 M92302 AAA35632 M92303 AAA35633 XM_005257645 XP_005257702 XM_005257646 XP_005257703 XM_005257647 XP_005257704 XM_006722072 XP_006722135 XM_011525186 XP_011523488 NM_000723 NP_000714 NM_199247 NP_954855 NM_199248 NP_954856
Function	The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Subcellular Location	Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity	Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle. {ECO:0000269|PubMed:8107964}.
Top Pathways	MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

L-type Ca ++ CP β1 siRNA (h) - sc-42694 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

L-type Ca ++ CP β1 shRNA Plasmid (h) - sc-42694-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

L-type Ca ++ CP β1 shRNA (h) Lentiviral Particles - sc-42694-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CACNB1 RNAi - H00000782-R01V from Novus Biologicals Category siRNA Prices $629.00 Sizes 20 nmol Species Reactivities Human

CACNB1 RNAi - H00000782-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU158411 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5269 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5269 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CACNB1 siRNA (Human) - CRH0547 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CACNB1 RNAi - H00000782-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

CACNB1 RNAi - H00000782-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CACNB1 - MBS8233351 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CACNB1 (NM_000723.4) - SHH253417 from Creative biogene Category siRNA Species Reactivities Human

Human CACNB1 siRNA - orb261049 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CACNB1 shRNA Plasmid (Human) - CHH0547 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CACNB1 miRNA 3'UTR clone - MiUTR3H-00322 from Creative biogene Species Reactivities Human

CACNB1 miRNA 3'UTR clone - MiUTR3H-00323 from Creative biogene Species Reactivities Human

CACNB1 miRNA 3'UTR clone - MiUTR3H-00324 from Creative biogene Species Reactivities Human

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