PHLDA2

Gene Symbol	PHLDA2
Entrez Gene	7262
Alt Symbol	BRW1C, BWR1C, HLDA2, IPL, TSSC3
Species	Human
Gene Type	protein-coding
Description	pleckstrin homology-like domain, family A, member 2
Other Description	beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein|imprinted in placenta and liver protein|p17-BWR1C|p17-Beckwith-Wiedemann region 1 C|p17-Beckwith-Wiedemann region 1C|pleckstrin homology-like domain family A member 2|tumor suppressing subchromosomal transferable fragment cDNA 3|tumor suppressing subtransferable candidate 3|tumor-suppressing STF cDNA 3 protein|tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein|tumor-supressing STF cDNA 3
Swissprots	O00496 Q53GA4
Accessions	EAX02531 Q53GA4 AF001294 AAB86680 AF019953 AAC51912 AF035444 AAC17458 AI659266 AK223027 BAD96747 BC005034 AAH05034 CR407664 CAG28592 HQ448329 ADQ32809 NM_003311 NP_003302
Function	Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity	Expressed in placenta and adult prostate gland. In placenta, it is present in all cells of the villous cytotrophoblast. The protein is absent in cells from hydatidiform moles. Hydatidiform mole is a gestation characterized by abnormal development of both fetus and trophoblast. The majority of hydatidiform moles are associated with an excess of paternal to maternal genomes and are likely to result from the abnormal expression of imprinted genes (at protein level). Expressed at low levels in adult liver and lung, and fetal liver. Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines. {ECO:0000269|PubMed:10594239, ECO:0000269|PubMed:10749982, ECO:0000269|PubMed:13129680, ECO:0000269|PubMed:15457853, ECO:0000269|PubMed:9328465}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TSSC3 full length protein - ab95505 from Abcam Category Protein Source E. coli Species Human

Human TSSC3 full length protein - ab173039 from Abcam Category Protein Source E. coli Species Human

Human TSSC3 peptide - ab23136 from Abcam Category Peptide Species Human

PHLDA2 / TSSC3 Antibody Blocking Peptide - LS-E3334 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PHLDA2 / TSSC3 Antibody Blocking Peptide - LS-E25645 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PHLDA2 / TSSC3 Antibody Blocking Peptide - LS-E21308 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PHLDA2 / TSSC3 Antibody Blocking Peptide - LS-E21309 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TSSC3 Partial Recombinant Protein - H00007262-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TSSC3 Protein - NBP1-44473 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

TSSC3 Recombinant Protein - P3550 from Novus Biologicals Category Protein Prices $669.00 Sizes 50 µg Species Human

PHLDA2-Antibody-C-term-Blocking-Peptide - BP14504b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TSSC3 blocking peptide - GTX25964-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

PHLDA2 Protein (OPPA01863) - OPPA01863 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human PHLDA2 protein - orb163482 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human Pleckstrin Homology-Like Domain Family Member 2 protein - orb81276 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

PHLDA2 Blocking Peptide - 33R-7668 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PHLDA2 protein (His tag) - 80R-1310 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

Human PHLDA2 Protein - abx068605 from Abbexa Category Protein Source E.coli Species Human

TSSC3 Peptide - AC21-0476-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PHLDA2 / TSSC3 (1-152, His-tag) - AR09456PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

PHLDA2 / TSSC3 (1-152, His-tag) - AR09456PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

PHLDA2 / TSSC3 - H00007262-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PHLDA2 / TSSC3 - H00007262-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PHLDA2 / TSSC3 - P3550 from Acris Antibodies Category Protein Prices $580.00 Sizes 50 µg Species Human

Pleckstrin homology-like domain family A member 2, Human Recombinant - 228-13224-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

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