CD8B

Gene Symbol	CD8B
Entrez Gene	926
Alt Symbol	CD8B1, LEU2, LY3, LYT3, P37
Species	Human
Gene Type	protein-coding
Description	CD8b molecule
Other Description	CD8 antigen, beta polypeptide 1 (p37)|T lymphocyte surface glycoprotein beta chain|T-cell surface glycoprotein CD8 beta chain
Swissprots	Q9UDB4 Q9UDB8 P14861 Q9UQ55 Q9UDB9 Q496E2 Q9UDB7 P10966 Q496E1 Q9UDC0 P14860 Q9UDB6 Q496E0 Q9UDB5 Q15980
Accessions	AAA52283 AAB21668 AAB21669 AAB21670 AAB21671 AAB21672 AAD13877 AAK91556 AAK91557 AAY24019 CCF76959 CCF76960 CCF76961 CCF76962 P10966 AK303360 BAG64420 AK303595 BAG64610 AW296309 AW611750 BC100911 AAI00912 BC100912 AAI00913 BC100913 AAI00914 BC100914 AAI00915 BP392114 BQ004743 DB223179 DC405359 M36712 AAA35664 X13444 CAA31795 X13445 CAA31796 X13446 CAA31797 X13452 CAA31803 Y00805 CAA68750 XM_011533164 XP_011531466 NM_001178100 NP_001171571 NM_004931 NP_004922 NM_172101 NP_742099 NM_172102 NP_742100 NM_172213 NP_757362 NM_172099
Function	Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.
Subcellular Location	Isoform 7: Secreted {ECO:0000305}.
Tissue Specificity	Isoform 1, isoform 3, isoform 5, isoform 6, isoform 7 and isoform 8 are expressed in both thymus and peripheral CD8+ T-cells. Expression of isoform 1 is higher in thymus CD8+ T-cells than in peripheral CD8+ T-cells. Expression of isoform 6 is higher in peripheral CD8+ T-cells than in thymus CD8+ T-cells. {ECO:0000269|PubMed:8436166}.
Top Pathways	Hematopoietic cell lineage, T cell receptor signaling pathway, Cell adhesion molecules (CAMs), Primary immunodeficiency, Antigen processing and presentation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CD8B-Over-expression-Lysate - LY12019a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

CD8B 293T Cell Transient Overexpression Lysate(Denatured) - H00000926-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CD8B overexpression lysate - LY406743 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CD8B overexpression lysate - LY432674 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CD8B 293 Cell Lysate - 404019 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CD8 beta Overexpression Lysate (Denatured) - H00000926-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

CD8B Over-expression Lysate Product - GWB-B82272 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Human CD8B / P37 / LEU2 HEK293 Cell Lysate (WB positive control) - 11031-HCCHL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD8B / P37 / LEU2 HEK293 Cell Lysate (WB positive control) - 11031-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CD8B Human Cells Transfected Lysate (positive control) (denatured) - orb174099 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

CD8 beta Overexpression Lysate (Native) - NBP2-05170 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CD8 beta Overexpression Lysate (Denatured) - H00000926-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Human CD8B Human Cells Transfected Lysate (positive control) (denatured) - orb179475 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human CD8B Knockdown Stable Cell Line - CSC-DC002780 from Creative biogene Category Cell Line Species Human

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