CD8B

Gene Symbol	CD8B
Entrez Gene	926
Alt Symbol	CD8B1, LEU2, LY3, LYT3, P37
Species	Human
Gene Type	protein-coding
Description	CD8b molecule
Other Description	CD8 antigen, beta polypeptide 1 (p37)|T lymphocyte surface glycoprotein beta chain|T-cell surface glycoprotein CD8 beta chain
Swissprots	Q9UDB4 Q9UDB8 P14861 Q9UQ55 Q9UDB9 Q496E2 Q9UDB7 P10966 Q496E1 Q9UDC0 P14860 Q9UDB6 Q496E0 Q9UDB5 Q15980
Accessions	AAA52283 AAB21668 AAB21669 AAB21670 AAB21671 AAB21672 AAD13877 AAK91556 AAK91557 AAY24019 CCF76959 CCF76960 CCF76961 CCF76962 P10966 AK303360 BAG64420 AK303595 BAG64610 AW296309 AW611750 BC100911 AAI00912 BC100912 AAI00913 BC100913 AAI00914 BC100914 AAI00915 BP392114 BQ004743 DB223179 DC405359 M36712 AAA35664 X13444 CAA31795 X13445 CAA31796 X13446 CAA31797 X13452 CAA31803 Y00805 CAA68750 XM_011533164 XP_011531466 NM_001178100 NP_001171571 NM_004931 NP_004922 NM_172101 NP_742099 NM_172102 NP_742100 NM_172213 NP_757362 NM_172099
Function	Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.
Subcellular Location	Isoform 7: Secreted {ECO:0000305}.
Tissue Specificity	Isoform 1, isoform 3, isoform 5, isoform 6, isoform 7 and isoform 8 are expressed in both thymus and peripheral CD8+ T-cells. Expression of isoform 1 is higher in thymus CD8+ T-cells than in peripheral CD8+ T-cells. Expression of isoform 6 is higher in peripheral CD8+ T-cells than in thymus CD8+ T-cells. {ECO:0000269|PubMed:8436166}.
Top Pathways	Hematopoietic cell lineage, T cell receptor signaling pathway, Cell adhesion molecules (CAMs), Primary immunodeficiency, Antigen processing and presentation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD8 beta full length protein - ab112264 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Human CD8 beta protein fragment - ab152059 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human CD8B protein fragment - ab114162 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CD8B protein fragment - ab177613 from Abcam Category Protein Prices $301.00 Sizes 100 µg Source E. coli Species Human

CD8B / CD8 Beta Antibody Blocking Peptide - LS-E1327 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD8B / CD8 Beta Antibody Blocking Peptide - LS-E3258 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD8B / CD8 Beta Antibody Blocking Peptide - LS-E15730 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD8B / CD8 Beta Antibody Blocking Peptide - LS-E15525 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD8 beta Partial Recombinant Protein - H00000926-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CD8 beta Recombinant Protein - H00000926-P01 from Novus Biologicals Category Protein Prices $309.00 Sizes 2 µg Species Human

CD8 beta Peptide - P0411 from Novus Biologicals Category Peptide Species Human

CD8B1-Antibody-C-term-Blocking-peptide - BP11957b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CD8B-Antibody-N-term-Blocking-peptide - BP1440a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CD8B protein - orb171613 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Human Cells Species Human

CD8b protein - orb197661 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Human CD8B protein - orb138497 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Human Cells Species Human

CD8 peptide - orb218804 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

CD8B Blocking Peptide - 33R-4582 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CD8B Blocking Peptide - 33R-7989 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CD8B Blocking Peptide - 33R-4815 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CD8B protein (His tag) - 80R-3653 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

CD8b Blocking Peptide - abx064135 from Abbexa Category Peptide Species Human, Mouse, Rat

Human CD8b Protein - abx065944 from Abbexa Category Protein Source E.coli Species Human

CD8 beta (22-170, His-tag) - AR51340PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CD8 beta (22-170, His-tag) - AR51340PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

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