EIF4E

Gene Symbol	EIF4E
Entrez Gene	1977
Alt Symbol	AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4E
Other Description	eIF-4E|eIF-4F 25 kDa subunit|eukaryotic translation initiation factor 4E-like 1|mRNA cap-binding protein
Swissprots	B7Z6V1 Q96E95 P06730 D6RCQ6
Accessions	AAB07114 CAI79364 CBL95069 CBY65608 CBY65610 EAX06077 EAX06078 EAX06079 EAX06080 EAX06081 P06730 AJ844638 AK295083 BAH11967 AK300982 BAH13387 AV708571 BC012611 AAH12611 BC035166 AAH35166 BC043226 AAH43226 BC107715 AAI07716 BM849222 CA419184 DC388666 DQ890728 ABM81654 DQ893903 ABM84829 KJ534830 AHW56470 M15353 AAC13647 XM_006714126 XP_006714189 XM_006714127 XP_006714190 NM_001130678 NP_001124150 NM_001130679 NP_001124151 NM_001968 NP_001959
Function	Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. {ECO:0000269|PubMed:16271312, ECO:0000269|PubMed:22578813}.
Subcellular Location	Cytoplasm, P-body {ECO:0000269|PubMed:20616046}. Cytoplasm {ECO:0000250}.
Top Pathways	Insulin signaling pathway, RNA transport, PI3K-Akt signaling pathway, mTOR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human eIF4E (mutated S53 A) full length protein - ab176929 from Abcam Category Protein Source E. coli Species Human

Human eIF4E full length protein - ab56276 from Abcam Category Protein Source E. coli Species Human

EIF4E Antibody Blocking Peptide - LS-E14716 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EIF4E Antibody Blocking Peptide - LS-E7393 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EIF4E Antibody Blocking Peptide - LS-E21550 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

eIF4E Recombinant Protein - H00001977-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human eIF4E Protein - NBP1-45314 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E.coli Species Human

eIF4E Peptide - P1608 from Novus Biologicals Category Peptide Species Human

Phospho-EIF4ES209-Antibody-Blocking-peptide - BP3474a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

EIF4E Protein (OPPA02445) - OPPA02445 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human Eukaryotic Translation Initiation Factor 4E protein - orb81081 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 2 μg, 10 μg Source E.coli Species Human

Eif4e Blocking Peptide - 33R-9310 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

EIF4E Blocking Peptide - 33R-9028 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

EIF4E protein (His tag) - 80R-1425 from Fitzgerald Category Protein Prices $395.00 Sizes 50 µg Source E.coli

EIF4E Blocking Peptide - abx062572 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Monkey, Rabbit

EIF4E (1-217, His-tag) - AR09601PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

EIF4E (1-217, His-tag) - AR09601PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

EIF4E - H00001977-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

EIF4E - H00001977-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EIF4E Control Peptide - AP09989CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

Eukaryotic Translation Initiation Factor 4E, Human Recombinant - 228-13104-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Eukaryotic Translation Initiation Factor 4E - 228-13104-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Eukaryotic Translation Initiation Factor 4E - 228-13104-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

EIF4E, 1-217aa, Human, His tag, E.coli - 01-1768-4E from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

EIF4E fusion protein - ag1626 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

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