| Gene Symbol |
ST6GALNAC4
|
| Entrez Gene |
27090
|
| Alt Symbol |
IV, SIAT3-C, SIAT3C, SIAT7-D, SIAT7D, ST6GALNACIV, ST6GalNAc
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
|
| Other Description |
NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2, 6-sialyltransferase alpha2,6-sialyltransferase|NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase IV|ST6 neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltransferase 4|ST6GalNAc IV|alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase|sialyltransferase 3C|sialyltransferase 7D ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase)
|
| Swissprots |
Q9UKU1 Q9H4F1 Q9NWU6 Q9Y3G4 Q5T9D0 Q9ULB9 Q9Y3G3
|
| Accessions |
AAF32237 CAB44353 CAB44354 CAS91685 EAW87717 EAW87718 EAW87719 EAW87720 EAW87721 Q9H4F1 AB035172 BAA87034 AJ271734 CAC07404 AK000600 BAA91281 AK292049 BAF84738 BC036705 AAH36705 CB126299 F27902 XM_011518527 XP_011516829 XM_011518528 XP_011516830 XM_011518529 XP_011516831 XM_011518530 XP_011516832 XR_929762 NM_175039 NP_778204 NM_175040 NP_778205 NM_014403
|
| Function |
Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. Prefers glycoproteins to glycolipids (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Glycosphingolipid biosynthesis - ganglio series
|
![Western Blot: ST6GALNAC4 Overexpression Lysate (Adult Normal) [NBL1-16501] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ST6GALNAC4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6102_ST6GALNAC4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16501-img0002.jpg)