Gene Symbol | ST6GALNAC4 |
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Entrez Gene | 27090 |
Alt Symbol | IV, SIAT3-C, SIAT3C, SIAT7-D, SIAT7D, ST6GALNACIV, ST6GalNAc |
Species | Human |
Gene Type | protein-coding |
Description | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
Other Description | NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2, 6-sialyltransferase alpha2,6-sialyltransferase|NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase IV|ST6 neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminidealpha-2,6-sialyltransferase 4|ST6GalNAc IV|alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase|sialyltransferase 3C|sialyltransferase 7D ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) |
Swissprots | Q9UKU1 Q9H4F1 Q9NWU6 Q9Y3G4 Q5T9D0 Q9ULB9 Q9Y3G3 |
Accessions | AAF32237 CAB44353 CAB44354 CAS91685 EAW87717 EAW87718 EAW87719 EAW87720 EAW87721 Q9H4F1 AB035172 BAA87034 AJ271734 CAC07404 AK000600 BAA91281 AK292049 BAF84738 BC036705 AAH36705 CB126299 F27902 XM_011518527 XP_011516829 XM_011518528 XP_011516830 XM_011518529 XP_011516831 XM_011518530 XP_011516832 XR_929762 NM_175039 NP_778204 NM_175040 NP_778205 NM_014403 |
Function | Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. Prefers glycoproteins to glycolipids (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Glycosphingolipid biosynthesis - ganglio series |
Sialyltransferase 7D (C-19) - sc-68810 from Santa Cruz Biotechnology
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Sialyltransferase 7D (D-24) - sc-133999 from Santa Cruz Biotechnology
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Anti-ST6GALNAC4 antibody - ab127016 from Abcam
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Anti-ST6GALNAC4 antibody - ab105559 from Abcam
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Anti-ST6GALNAC4 antibody - C-terminal - ab139126 from Abcam
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Anti-ST6GALNAC4 Antibody (aa181-209) - LS-C157100 from LifeSpan Bioscience
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Anti-ST6GALNAC4 Antibody - LS-C155615 from LifeSpan Bioscience
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Anti-ST6GALNAC4 Antibody (aa181-209, AP) - LS-C217758 from LifeSpan Bioscience
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Anti-ST6GALNAC4 Antibody (aa181-209, APC) - LS-C217759 from LifeSpan Bioscience
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Anti-ST6GALNAC4 Antibody (aa181-209, Biotin) - LS-C217760 from LifeSpan Bioscience
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Anti-ST6GALNAC4 Antibody (aa181-209, FITC) - LS-C217761 from LifeSpan Bioscience
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Anti-ST6GALNAC4 Antibody (aa181-209, Azide-free, HRP) - LS-C217762 from LifeSpan Bioscience
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Anti-ST6GALNAC4 Antibody (aa181-209, PE) - LS-C217763 from LifeSpan Bioscience
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Anti-ST6GALNAC4 Antibody (aa181-209) - LS-C325416 from LifeSpan Bioscience
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ST6GALNAC4 Antibody - NBP1-62417 from Novus Biologicals
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ST6GALNAC4 Antibody - NBP1-80752 from Novus Biologicals
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ST6GALNAC4 Antibody - NBP2-20495 from Novus Biologicals
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Anti-ST6GALNAC4 antibody produced in rabbit - SAB2701445 from Sigma-Aldrich
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Anti-ST6GALNAC4 antibody produced in rabbit - AV49121 from Sigma-Aldrich
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Anti-ST6GALNAC4 antibody produced in rabbit - HPA009042 from Sigma-Aldrich
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ST6GALNAC4 antibody - middle region (ARP49121_P050) - ARP49121_P050 from Aviva Systems Biology
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ST6GALNAC4-Antibody-C-term - AP18979b from Abgent, a WuXi AppTec company
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ST6GALNAC4 Antibody - C-terminal region (OAAB14517) - OAAB14517 from Aviva Systems Biology
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ST6GALNAC4 antibody - 70R-7277 from Fitzgerald
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ST6GALNAC4 Antibody - abx030687 from Abbexa
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