TFEB

Gene Symbol TFEB
Entrez Gene 7942
Alt Symbol ALPHATFEB, BHLHE35, TCFEB
Species Human
Gene Type protein-coding
Description transcription factor EB
Other Description T-cell transcription factor EB|class E basic helix-loop-helix protein 35
Swissprots Q7Z6P9 Q9BRJ5 Q9UJD8 Q709B3 P19484
Accessions CAD59560 EAX04055 EAX04056 EAX04057 EAX04058 P19484 AA235980 AJ608786 CAE77681 AJ608787 CAE77672 AJ608788 CAE77673 AJ608789 CAE77674 AJ608790 CAE77675 AJ608791 CAE77676 AJ608792 CAE77677 AJ608793 CAE77678 AJ608794 CAE77679 AK095061 BAG52979 AK298390 BAG60625 AK310063 AW294760 BC006225 AAH06225 BC032448 AAH32448 BU527754 CT000098 EU446667 ABZ92196 M33782 AAA36730 XM_005249411 XP_005249468 XM_005249412 XP_005249469 XM_006715212 XP_006715275 XM_006715213 XP_006715276 XM_011514915 XP_011513217 XM_011514916 XP_011513218 NM_001167827 NP_001161299 NM_001271943 NP_001258872 NM_001271944 NP_001258873 NM_001271945 NP_001258874 NM_007162 NP_009093
Function Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. {ECO:0000269|PubMed:19556463, ECO:00
Subcellular Location Cytoplasm. Nucleus. Note=Mainly present in the cytoplasm. Under aberrant lysosomal storage conditions, it translocates from the cytoplasm to the nucleus.

TFEB Antibody - 4240 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Raji cells, untreated (-) or Torin1-treated (250 nM, 1 hr; +), using TFEB Antibody.

TFEB (C-6) - sc-166736 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TFEB (C-6): sc-166736. Western blot analysis of TFEB expression in non-transfected: sc-117752 (A) and human TFEB transfected: sc-114904 (B) 293T whole cell lysates.

TFEB (H-125) - sc-48784 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TFEB (H-125): sc-48784. Western blot analysis of TFEB expression in non-transfected: sc-117752 (A) and human TFEB transfected: sc-114904 (B) 293T whole cell lysates.

TFEB (17) - sc-101532 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TFEB (17): sc-101532. Western blot analysis of TFEB expression in HeLa whole cell lysate.

TFEB (A-16) - sc-11005 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TFEB (A-16): sc-11005. Western blot analysis of TFEB expression in non-transfected: sc-117752 (A) and human TFEB transfected: sc-114904 (B) 293T whole cell lysates.

TFEB (V-17) - sc-11004 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TFEB antibody - ab181342 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of Human lung tissue labeling TFEB with ab181342 at 20 µg/ml.

Anti-TFEB antibody - ab96834 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-TFEB antibody (ab96834) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-TFEB antibody [319C2a] - ab70729 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 319C2a
Anti-TFEB antibody [319C2a] (ab70729) + immunising recombinant protein

Anti-TFEB antibody - N-terminal - ab174745 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded formalin fixed Human skin tissue labeling TFEB using ab174745 at 5 µg/ml.

Anti-TFEB Antibody (clone 319C2a) - LS-C342677 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 319C2a
Western blot analysis of immunized recombinant protein, using anti-TFEB monoclonal antibody.

Anti-TFEB Antibody - LS-C346356 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of MCF7 cell using TFEB antibody. Blue: DAPI for nuclear staining.

Anti-TFEB Antibody (N-Terminus) IHC-plus™ - LS-B5907 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TFEB antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5907 concentration 5 ug/ml.

Anti-TFEB Antibody IHC-plus™ - LS-B7815 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TFEB antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7815 dilution 5 ug/ml.

Anti-TFEB Antibody (clone S1) - LS-C198513 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S1
Immunofluorescence of monoclonal antibody to TFEB on HeLa cell. [antibody concentration 20 ug/ml]

Anti-TFEB Antibody (aa426-476) - LS-C290335 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human TFEB by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-TFEB used at a dilution of 1:1000 (1 Detection: DAB.

Anti-TFEB Antibody (N-Terminus) IHC-plus™ - LS-B8820 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TFEB antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TFEB Antibody - LS-C10837 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TFEB Antibody - LS-C76485 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-TFEB Antibody (aa87-103) - LS-C147953 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-TFEB Antibody (C-Terminus) - LS-C31138 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: HepG2 Cell Lysate

Anti-TFEB Antibody (aa170-219) - LS-C30060 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 Cell Lysate

Anti-TFEB Antibody (aa285-300) - LS-C148010 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-TFEB Antibody (aa220-238) - LS-C148007 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-TFEB Antibody - LS-C137533 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Search more