TFEB

Gene Symbol	TFEB
Entrez Gene	7942
Alt Symbol	ALPHATFEB, BHLHE35, TCFEB
Species	Human
Gene Type	protein-coding
Description	transcription factor EB
Other Description	T-cell transcription factor EB|class E basic helix-loop-helix protein 35
Swissprots	Q7Z6P9 Q9BRJ5 Q9UJD8 Q709B3 P19484
Accessions	CAD59560 EAX04055 EAX04056 EAX04057 EAX04058 P19484 AA235980 AJ608786 CAE77681 AJ608787 CAE77672 AJ608788 CAE77673 AJ608789 CAE77674 AJ608790 CAE77675 AJ608791 CAE77676 AJ608792 CAE77677 AJ608793 CAE77678 AJ608794 CAE77679 AK095061 BAG52979 AK298390 BAG60625 AK310063 AW294760 BC006225 AAH06225 BC032448 AAH32448 BU527754 CT000098 EU446667 ABZ92196 M33782 AAA36730 XM_005249411 XP_005249468 XM_005249412 XP_005249469 XM_006715212 XP_006715275 XM_006715213 XP_006715276 XM_011514915 XP_011513217 XM_011514916 XP_011513218 NM_001167827 NP_001161299 NM_001271943 NP_001258872 NM_001271944 NP_001258873 NM_001271945 NP_001258874 NM_007162 NP_009093
Function	Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. {ECO:0000269|PubMed:19556463, ECO:00
Subcellular Location	Cytoplasm. Nucleus. Note=Mainly present in the cytoplasm. Under aberrant lysosomal storage conditions, it translocates from the cytoplasm to the nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

transcription factor EB, ELISA Kit - MBS9337615 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml. Range 0.25 ng/ml - 8 ng/ml.

Human TFEB ELISA Kit - E100132 from Biobool Category ELISA Kit

anti-TFEB antibody - ARG63210 from Arigo Biolaboratories Category ELISA Kit

anti-TFEB antibody - ARG64569 from Arigo Biolaboratories Category ELISA Kit

Transcription Factor EB (TFEB), ELISA Kit - MBS9348448 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9363859 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9367066 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9345597 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9357879 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9344814 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9363658 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9357067 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9350570 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9355717 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9368034 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9360063 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9352650 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9354809 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9356202 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9345677 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9380761 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9357497 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9363079 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9346315 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor EB (TFEB), ELISA Kit - MBS9354320 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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