AGK

Gene Symbol AGK
Entrez Gene 55750
Alt Symbol CATC5, CTRCT38, MTDPS10, MULK
Species Human
Gene Type protein-coding
Description acylglycerol kinase
Other Description acylglycerol kinase, mitochondrial|hAGK|hsMuLK|multi-substrate lipid kinase|multiple substrate lipid kinase
Swissprots Q96GC3 Q75KN1 Q53H12 Q9NP48
Accessions AAS07537 AAS07538 CAE89682 EAL24020 EAW83972 EAW83973 Q53H12 AJ278150 CAB93536 AK001704 BAA91848 AK222769 BAD96489 AK299131 BAG61184 AK304502 BAG65310 BC009775 AAH09775 BC022777 AAH22777 DB032353 XM_005250023 XP_005250080 XM_011516397 XP_011514699 NM_018238 NP_060708
Function Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth. {ECO:0000269|PubMed:15939762}.
Subcellular Location Mitochondrion membrane {ECO:0000269|PubMed:15939762, ECO:0000269|PubMed:16269826}.
Tissue Specificity Highly expressed in muscle, heart, kidney and brain. {ECO:0000269|PubMed:15939762}.
Top Pathways Glycerolipid metabolism

MULK (C-7) - sc-398943 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MULK (C-7): sc-398943. Western blot analysis of MULK expression in non-transfected 293T: sc-117752 (A), human MULK transfected 293T: sc-113678 (B), MOLT-4 (C), PC-3 (D) and HL-60 (E) whole cell lysates.

MULK (F-3) - sc-374390 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MULK (F-3): sc-374390. Western blot analysis of MULK expression in MOLT-4 (A), PC-3 (B) and HL-60 (C) whole cell lysates.

MULK (F-5) - sc-514235 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MULK (F-5): sc-514235. Western blot analysis of MULK expression in non-transfected 293T: sc-117752 (A), human MULK transfected 293T: sc-113678 (B), MOLT-4 (C) and HL-60 (D) whole cell lysates.

MULK (E-19) - sc-160548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MULK (E-19): sc-160548. Western blot analysis of MULK expression in SW480 (A), Raji (B), HL-60 (C) and MOLT-4 (D) whole cell lysates.

MULK (C-16) - sc-160547 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MULK (C-16): sc-160547. Western blot analysis of MULK expression in Raji (A), HL-60 (B) and MOLT-4 (C) whole cell lysates.

Anti-Acylglycerol Kinase antibody - ab137616 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Acylglycerol Kinase antibody (ab137616) at 1/500 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Acylglycerol Kinase antibody - ab107607 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Acylglycerol Kinase antibody (ab107607) at 1/500 dilutionLane 1 : Human Fetal Brain lysateLane 2 : Human Fetal Heart lysateLane 3 : Human Fetal Kidney lysateLane 4 : Human Fetal Lung lysate

Anti-Acylglycerol Kinase antibody - ab77266 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Acylglycerol Kinase antibody (ab77266) at 1 µg/ml + Human Brain (Substantia nigra) lysate in RIPA buffer at 35 µg

Anti-Acylglycerol Kinase antibody - ab95094 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Acylglycerol Kinase antibody (ab95094) at 1/100 dilution + K562 cell lysate at 35 µg

Anti-Acylglycerol Kinase antibody - ab67806 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-Acylglycerol Kinase antibody (ab67806) at 1/500 dilutionLane 1 : Acylglycerol Kinase transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

Anti-AGK Antibody - LS-C306128 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AGK Antibody (aa107-156) - LS-C111992 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AGK antibody LS-C111992 Western blot of Fetal Brain lysate.

Anti-AGK Antibody (aa35-84) - LS-C135427 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AGK antibody LS-C135427 Western blot of Transfected 293T cell lysate.

Anti-AGK Antibody (aa408-420) - LS-C54446 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1 ug/ml) staining of Human Brain (Substantia nigra) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Acylglycerol Kinase Antibody - NBP1-32163 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Acylglycerol Kinase Antibody - NBP1-83825 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Acylglycerol Kinase Antibody [NBP1-83825] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp

Acylglycerol Kinase Antibody - NBP1-06013 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: Acylglycerol Kinase Antibody [NBP1-06013] - Analysis of Acylglycerol Kinase using NBP1-06013 at 1ug/ml in Human Brain (Substantia nigra) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Acylglycerol Kinase Antibody - H00055750-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Acylglycerol Kinase Antibody [H00055750-B01] - analysis of MULK expression in transfected 293T cell line by MULK MaxPab polyclonal antibody (B01). Lane 1: MULK transfected lysate (47.10 KDa). Lane 2: Non-transfected lysate.

Acylglycerol Kinase Antibody - H00055750-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Acylglycerol Kinase Antibody [H00055750-B01P] - Analysis of AGK expression in transfected 293T cell line by AGK polyclonal antibody. Lane 1: MULK transfected lysate(46.42 KDa). Lane 2: Non-transfected lysate.

Acylglycerol Kinase Polyclonal Antibody - bs-6276R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded mouse brain labeled with Rabbit Anti Acylglycerol Kinase Polyclonal Antibody, Unconjugated (bs-6276R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-AGK antibody produced in rabbit - HPA053471 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AGK: <B>Cat. No. HPA053471</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Anti-AGK antibody produced in rabbit - HPA020959 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AGK: <B>Cat. No. HPA020959</B>: Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity.

Anti-AGK (96-110) antibody produced in rabbit - A3732 from Sigma-Aldrich

Prices $342.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-AGK (96-110) : <B>Cat. No. A3732</B>: Immunofluorescence of HUVEC cells using Anti-AGK (96-110) (red) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used.

Anti-AGK antibody produced in mouse - SAB1407688 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AGK: <B>Cat. No. SAB1407688</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~46.4 kDa using AGK transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-Acylglycerol kinase antibody produced in goat - SAB2500025 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Acylglycerol kinase: <B>Cat. No. SAB2500025</B>: (1 μg/mL) staining of Human Brain (Substantia nigra) lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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