AGK

Gene Symbol AGK
Entrez Gene 55750
Alt Symbol CATC5, CTRCT38, MTDPS10, MULK
Species Human
Gene Type protein-coding
Description acylglycerol kinase
Other Description acylglycerol kinase, mitochondrial|hAGK|hsMuLK|multi-substrate lipid kinase|multiple substrate lipid kinase
Swissprots Q96GC3 Q75KN1 Q53H12 Q9NP48
Accessions AAS07537 AAS07538 CAE89682 EAL24020 EAW83972 EAW83973 Q53H12 AJ278150 CAB93536 AK001704 BAA91848 AK222769 BAD96489 AK299131 BAG61184 AK304502 BAG65310 BC009775 AAH09775 BC022777 AAH22777 DB032353 XM_005250023 XP_005250080 XM_011516397 XP_011514699 NM_018238 NP_060708
Function Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth. {ECO:0000269|PubMed:15939762}.
Subcellular Location Mitochondrion membrane {ECO:0000269|PubMed:15939762, ECO:0000269|PubMed:16269826}.
Tissue Specificity Highly expressed in muscle, heart, kidney and brain. {ECO:0000269|PubMed:15939762}.
Top Pathways Glycerolipid metabolism

MULK CRISPR/Cas9 KO Plasmid (h) - sc-406375 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MULK HDR Plasmid (h) - sc-406375-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MULK Double Nickase Plasmid (h) - sc-406375-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MULK Double Nickase Plasmid (h2) - sc-406375-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MULK CRISPR Activation Plasmid (h) - sc-406375-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MULK CRISPR Activation Plasmid (h2) - sc-406375-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MULK Lentiviral Activation Particles (h) - sc-406375-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MULK Lentiviral Activation Particles (h2) - sc-406375-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MULK siRNA (h) - sc-89394 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MULK shRNA Plasmid (h) - sc-89394-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MULK shRNA (h) Lentiviral Particles - sc-89394-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Acylglycerol Kinase RNAi - H00055750-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU115101 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0070 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0072 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0071 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2945 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2945 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AGK siRNA (Human) - CRJ0888 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGK - MBS8229568 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AGK (NM_018238.3) - SHH233278 from Creative biogene

Category siRNA
Species Reactivities Human

Human AGK siRNA - orb271389 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGK shRNA Plasmid (Human) - CHJ0888 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AGK miRNA 3'UTR clone - MiUTR3H-11173 from Creative biogene

Species Reactivities Human
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