PCNT

Gene Symbol PCNT
Entrez Gene 5116
Alt Symbol KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4
Species Human
Gene Type protein-coding
Description pericentrin
Other Description kendrin|pericentrin-2|pericentrin-380|pericentrin-B
Swissprots O43152 Q7Z7C9 O95613
Accessions CBX47507 EAX09277 EAX09278 EAX09279 EAX09280 EAX09281 O95613 AB007862 BAA23698 AF515282 AAP46636 AK024009 BAB14772 AK093923 BAC04252 AK296731 BAG59318 AW452809 BC035913 AAH35913 BP311784 BP312870 DC345793 U52962 AAD10838 XM_005261124 XP_005261181 XM_005261129 XP_005261186 XM_011529593 XP_011527895 XM_011529594 XP_011527896 NM_006031 NP_006022
Function Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome. {ECO:0000269|PubMed:10823944, ECO:0000269|PubMed:11171385, ECO:0000269|PubMed:18955030, ECO:0000269|PubMed:20599736}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:10823944, ECO:0000269|PubMed:11171385, ECO:0000269|PubMed:18955030, ECO:0000269|PubMed:22797915}. Note=Centrosomal at all stages of the cell cycle. Remains associated with centrosomes following microtubule depolymerization. Colocalized with DISC1 at the centrosome.
Tissue Specificity Expressed in all tissues tested, including placenta, liver, kidney and thymus. {ECO:0000269|PubMed:10823944}.

Pericentrin 2 CRISPR/Cas9 KO Plasmid (h) - sc-401822 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pericentrin 2 HDR Plasmid (h) - sc-401822-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pericentrin 2 Double Nickase Plasmid (h) - sc-401822-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pericentrin 2 Double Nickase Plasmid (h2) - sc-401822-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pericentrin 2 CRISPR Activation Plasmid (h) - sc-401822-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pericentrin 2 CRISPR Activation Plasmid (h2) - sc-401822-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pericentrin 2 Lentiviral Activation Particles (h) - sc-401822-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pericentrin 2 Lentiviral Activation Particles (h2) - sc-401822-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pericentrin 2 siRNA (h) - sc-45456 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pericentrin 2 shRNA Plasmid (h) - sc-45456-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pericentrin 2 shRNA (h) Lentiviral Particles - sc-45456-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16488 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16488 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05488 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05488

PCNT siRNA (Human) - CRH3402 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PCNT (NM_006031.5) - SHH371928 from Creative biogene

Category siRNA
Species Reactivities Human

Human PCNT siRNA - orb263904 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PCNT shRNA Plasmid (Human) - CHH3402 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PCNT miRNA 3'UTR clone - MiUTR3H-08052 from Creative biogene

Species Reactivities Human
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