MTRR

Gene Symbol	MTRR
Entrez Gene	4552
Alt Symbol	MSR, cblE
Species	Human
Gene Type	protein-coding
Description	5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Other Description	[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing)|methionine synthase reductase|methionine synthase reductase, mitochondrial
Swissprots	Q32MA9 Q9UBK8 Q7Z4M8 O60471
Accessions	AAF17303 AAF17304 EAX08090 EAX08091 EAX08092 EAX08093 Q9UBK8 AF025794 AAC39667 AF121214 AAF16876 AK308442 AK311663 BC035977 BC054816 AAH54816 BC062577 BC109216 AAI09217 BC109217 XM_006714474 XP_006714537 XM_011514043 XP_011512345 XM_011514044 XP_011512346 XM_011514045 XP_011512347 XR_241702 XR_241703 XR_925614 XR_925615 NM_002454 NP_002445 NM_024010 NP_076915
Function	Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary for utilization of methylgroups from the folate cycle, thereby affecting transgenerational epigenetic inheritance. Folate pathway donates methyl groups necessary for cellular methylation and affects different pathways such as DNA methylation, possibly explaining the transgenerational epigenetic inheritance effects. {ECO:0000269|PubMed:17892308}.
Subcellular Location	Isoform A: Cytoplasm {ECO:0000269|PubMed:18221906}.
Tissue Specificity	Found in all tissues tested, particularly abundant in skeletal muscle.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MTRR Gene cDNA Clone - orb144339 from Biorbyt Prices $366.00 Sizes 10 μg Species Human

Human-MTRR-cDNA-Clone - DC09554 from Abgent, a WuXi AppTec company Prices $942.30 Sizes 10 µg Species Human Accession BC054816

MTRR - MBS1276982 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC054816

MTRR - MBS1267366 from MyBioSource Species Human Accession BC109216

Human MTRR Gene ORF cDNA clone in cloning vector - HG15962-G from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15962-NM from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15962-CM from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, C-HA tag - HG15962-CY from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15962-ACG from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15962-ACR from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15962-ANR from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15962-ANG from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, N-HA tag - HG15962-NY from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15962-NF from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, C-His tag - HG15962-CH from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, N-His tag - HG15962-NH from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid - HG15962-UT from Sino Biological Species Human

Human MTRR Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15962-CF from Sino Biological Species Human

Mouse MTRR ORF clone (NM_002454.2) - CDCL135207 from Creative biogene Species Human

Human MTRR ORF Clone (BC109216) - CDCS410806 from Creative biogene Species Human Accession Q9UBK8

Human MTRR ORF Clone (BC054816) - CDCS410807 from Creative biogene Species Human Accession Q9UBK8

Human MTRR ORF clone (BC109216) - CDCB157619 from Creative biogene Species Human

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