MTRR

Gene Symbol MTRR
Entrez Gene 4552
Alt Symbol MSR, cblE
Species Human
Gene Type protein-coding
Description 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Other Description [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing)|methionine synthase reductase|methionine synthase reductase, mitochondrial
Swissprots Q32MA9 Q9UBK8 Q7Z4M8 O60471
Accessions AAF17303 AAF17304 EAX08090 EAX08091 EAX08092 EAX08093 Q9UBK8 AF025794 AAC39667 AF121214 AAF16876 AK308442 AK311663 BC035977 BC054816 AAH54816 BC062577 BC109216 AAI09217 BC109217 XM_006714474 XP_006714537 XM_011514043 XP_011512345 XM_011514044 XP_011512346 XM_011514045 XP_011512347 XR_241702 XR_241703 XR_925614 XR_925615 NM_002454 NP_002445 NM_024010 NP_076915
Function Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary for utilization of methylgroups from the folate cycle, thereby affecting transgenerational epigenetic inheritance. Folate pathway donates methyl groups necessary for cellular methylation and affects different pathways such as DNA methylation, possibly explaining the transgenerational epigenetic inheritance effects. {ECO:0000269|PubMed:17892308}.
Subcellular Location Isoform A: Cytoplasm {ECO:0000269|PubMed:18221906}.
Tissue Specificity Found in all tissues tested, particularly abundant in skeletal muscle.

MSR CRISPR/Cas9 KO Plasmid (h) - sc-409650 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSR HDR Plasmid (h) - sc-409650-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSR Double Nickase Plasmid (h) - sc-409650-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSR Double Nickase Plasmid (h2) - sc-409650-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSR CRISPR Activation Plasmid (h) - sc-409650-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSR CRISPR Activation Plasmid (h2) - sc-409650-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSR Lentiviral Activation Particles (h) - sc-409650-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSR Lentiviral Activation Particles (h2) - sc-409650-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSR siRNA (h) - sc-61078 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSR shRNA Plasmid (h) - sc-61078-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSR shRNA (h) Lentiviral Particles - sc-61078-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MTRR RNAi - H00004552-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MTRR RNAi - H00004552-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU070551 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2086 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2086 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07684 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07684

MTRR siRNA (Human) - CRH3017 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MTRR (NM_002454.2) - SHH346720 from Creative biogene

Category siRNA
Species Reactivities Human

MTRR shRNA Plasmid (Human) - CHH3017 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MTRR miRNA 3'UTR clone - MiUTR3H-05084 from Creative biogene

Species Reactivities Human

MTRR miRNA 3'UTR clone - MiUTR3H-05085 from Creative biogene

Species Reactivities Human
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