| Gene Symbol |
GLRA3
|
| Entrez Gene |
8001
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glycine receptor, alpha 3
|
| Other Description |
glycine receptor subunit alpha-3|glycine receptor, alpha-3 polypeptide|ligand gated ion channel
|
| Swissprots |
O75816 O75311 Q5D0E3 D3DP44
|
| Accessions |
AAC39919 AAY40916 EAX04730 EAX04731 EAX04732 EAX04733 O75311 AF018157 AAC39918 BC036086 AAH36086 BI600831 CV381684 DA409556 DQ890974 ABM81900 DQ894148 ABM85074 U93917 AAC39917 XM_011532266 XP_011530568 XM_011532267 XP_011530569 XM_011532268 XP_011530570 NM_001042543 NP_001036008 NM_006529 NP_006520
|
| Function |
The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Widely distributed throughout the central nervous system.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|
![Western Blot: Glycine Receptor alpha 3 Overexpression Lysate (Adult Normal) [NBP2-04313] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Glycine Receptor alpha 3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8739_Glycine%2520Receptor%2520alpha%25203%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04313-img0001.jpg)