Gene Symbol | GLRA3 |
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Entrez Gene | 8001 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | glycine receptor, alpha 3 |
Other Description | glycine receptor subunit alpha-3|glycine receptor, alpha-3 polypeptide|ligand gated ion channel |
Swissprots | O75816 O75311 Q5D0E3 D3DP44 |
Accessions | AAC39919 AAY40916 EAX04730 EAX04731 EAX04732 EAX04733 O75311 AF018157 AAC39918 BC036086 AAH36086 BI600831 CV381684 DA409556 DQ890974 ABM81900 DQ894148 ABM85074 U93917 AAC39917 XM_011532266 XP_011530568 XM_011532267 XP_011530569 XM_011532268 XP_011530570 NM_001042543 NP_001036008 NM_006529 NP_006520 |
Function | The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Widely distributed throughout the central nervous system. |
Top Pathways | Neuroactive ligand-receptor interaction |
GlyR α3 CRISPR/Cas9 KO Plasmid (h) - sc-403621 from Santa Cruz Biotechnology
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GlyR α3 HDR Plasmid (h) - sc-403621-HDR from Santa Cruz Biotechnology
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GlyR α3 Double Nickase Plasmid (h) - sc-403621-NIC from Santa Cruz Biotechnology
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GlyR α3 Double Nickase Plasmid (h2) - sc-403621-NIC-2 from Santa Cruz Biotechnology
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GlyR α3 CRISPR Activation Plasmid (h) - sc-403621-ACT from Santa Cruz Biotechnology
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GlyR α3 CRISPR Activation Plasmid (h2) - sc-403621-ACT-2 from Santa Cruz Biotechnology
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GlyR α3 Lentiviral Activation Particles (h) - sc-403621-LAC from Santa Cruz Biotechnology
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GlyR α3 Lentiviral Activation Particles (h2) - sc-403621-LAC-2 from Santa Cruz Biotechnology
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GlyR α3 siRNA (h) - sc-42469 from Santa Cruz Biotechnology
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GlyR α3 shRNA Plasmid (h) - sc-42469-SH from Santa Cruz Biotechnology
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GlyR α3 shRNA (h) Lentiviral Particles - sc-42469-V from Santa Cruz Biotechnology
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Glycine Receptor alpha 3 RNAi - H00008001-R01 from Novus Biologicals
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MISSION® esiRNA - EHU082561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9355 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9355 from Sigma-Aldrich
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GLRA3 siRNA (Human) - CRH5338 from Cohesion Biosciences
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GLRA3 - MBS8216233 from MyBioSource
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shRNA set against Human GLRA3(NM_001042543.1) - SHH087563 from Creative biogene
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shRNA set against Human GLRA3(NM_006529.2) - SHH087581 from Creative biogene
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Human GLRA3 siRNA - orb265840 from Biorbyt
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GLRA3 shRNA Plasmid (Human) - CHH5338 from Cohesion Biosciences
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GLRA3 miRNA 3'UTR clone - MiUTR1H-04072 from Creative biogene
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GLRA3 miRNA 3'UTR clone - MiUTR1H-04073 from Creative biogene
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