Gene Symbol | GLRA3 |
---|---|
Entrez Gene | 8001 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | glycine receptor, alpha 3 |
Other Description | glycine receptor subunit alpha-3|glycine receptor, alpha-3 polypeptide|ligand gated ion channel |
Swissprots | O75816 O75311 Q5D0E3 D3DP44 |
Accessions | AAC39919 AAY40916 EAX04730 EAX04731 EAX04732 EAX04733 O75311 AF018157 AAC39918 BC036086 AAH36086 BI600831 CV381684 DA409556 DQ890974 ABM81900 DQ894148 ABM85074 U93917 AAC39917 XM_011532266 XP_011530568 XM_011532267 XP_011530569 XM_011532268 XP_011530570 NM_001042543 NP_001036008 NM_006529 NP_006520 |
Function | The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Widely distributed throughout the central nervous system. |
Top Pathways | Neuroactive ligand-receptor interaction |