| Gene Symbol |
IFT27
|
| Entrez Gene |
11020
|
| Alt Symbol |
BBS19, RABL4, RAYL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
intraflagellar transport 27
|
| Other Description |
RAB, member of RAS oncogene family-like 4|intraflagellar transport protein 27 homolog|rab-like protein 4
|
| Swissprots |
O60897 Q9BW83
|
| Accessions |
EAW60114 EAW60115 EAW60116 EAW60117 Q9BW83 AA809074 AB209424 BAD92661 AI215119 AK090708 AK307105 AK307382 AL022729 CAA18787 AW236857 BC000566 AAH00566 BM711121 BT006815 AAP35461 BX537634 CR456558 CAG30444 CU013158 CAK54589 CU013446 CAK54888 DB457924 DB502180 XM_006724106 XP_006724169 NM_001177701 NP_001171172 NM_006860 NP_006851 NR_033531 NM_001177702
|
| Function |
Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 (PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 (PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25 (By similarity). {ECO:0000250|UniProtKB:A8HN58, ECO:0000269|PubMed:25443296}.
|
| Subcellular Location |
Cell projection, cilium {ECO:0000269|PubMed:25443296}.
|