Gene Symbol | IFT27 |
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Entrez Gene | 11020 |
Alt Symbol | BBS19, RABL4, RAYL |
Species | Human |
Gene Type | protein-coding |
Description | intraflagellar transport 27 |
Other Description | RAB, member of RAS oncogene family-like 4|intraflagellar transport protein 27 homolog|rab-like protein 4 |
Swissprots | O60897 Q9BW83 |
Accessions | EAW60114 EAW60115 EAW60116 EAW60117 Q9BW83 AA809074 AB209424 BAD92661 AI215119 AK090708 AK307105 AK307382 AL022729 CAA18787 AW236857 BC000566 AAH00566 BM711121 BT006815 AAP35461 BX537634 CR456558 CAG30444 CU013158 CAK54589 CU013446 CAK54888 DB457924 DB502180 XM_006724106 XP_006724169 NM_001177701 NP_001171172 NM_006860 NP_006851 NR_033531 NM_001177702 |
Function | Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 (PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 (PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25 (By similarity). {ECO:0000250|UniProtKB:A8HN58, ECO:0000269|PubMed:25443296}. |
Subcellular Location | Cell projection, cilium {ECO:0000269|PubMed:25443296}. |
Rab L4 (S-12) - sc-86204 from Santa Cruz Biotechnology
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Rab L4 (T-14) - sc-86205 from Santa Cruz Biotechnology
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Anti-RABL4 antibody - ab67909 from Abcam
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Anti-RABL4 antibody - C-terminal - ab173684 from Abcam
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Anti-IFT27 / RABL4 Antibody (aa156-183, AP) - LS-C222850 from LifeSpan Bioscience
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Anti-IFT27 / RABL4 Antibody (aa156-183, FITC) - LS-C222854 from LifeSpan Bioscience
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Anti-IFT27 / RABL4 Antibody (aa156-183, PE) - LS-C222856 from LifeSpan Bioscience
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Anti-IFT27 / RABL4 Antibody (aa156-183, APC) - LS-C222852 from LifeSpan Bioscience
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Anti-IFT27 / RABL4 Antibody (aa156-183, Azide-free, HRP) - LS-C222855 from LifeSpan Bioscience
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Anti-IFT27 / RABL4 Antibody (aa156-183, Biotin) - LS-C222853 from LifeSpan Bioscience
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Anti-IFT27 / RABL4 Antibody (aa156-183) - LS-C322162 from LifeSpan Bioscience
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Anti-IFT27 / RABL4 Antibody (aa157-183) - LS-C159887 from LifeSpan Bioscience
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Anti-IFT27 / RABL4 Antibody (C-Terminus) - LS-C81211 from LifeSpan Bioscience
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RABL4 Antibody - NBP1-87170 from Novus Biologicals
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RABL4 Antibody - NBP1-58928 from Novus Biologicals
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RABL4 Antibody - H00011020-B01 from Novus Biologicals
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RABL4 Antibody - H00011020-B01P from Novus Biologicals
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Anti-IFT27 antibody produced in rabbit - HPA018418 from Sigma-Aldrich
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Anti-RABL4 antibody produced in mouse - SAB1407089 from Sigma-Aldrich
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Anti-RABL4 antibody produced in rabbit - AV48306 from Sigma-Aldrich
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RABL4 antibody - C-terminal region (ARP48306_P050) - ARP48306_P050 from Aviva Systems Biology
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IFT27-Antibody-C-term - AP17978b from Abgent, a WuXi AppTec company
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IFT27 Antibody - C-terminal region (OAAB13407) - OAAB13407 from Aviva Systems Biology
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Anti -IFT27 (Intraflagellar Transport Protein 27 Homolog, Putative GTP-binding ProteinRAY-like, Rab-like Protein 4, RABL4, RAYL) - 132244 from USBiological Life Science
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Anti -IFT27, CT (IFT27, RABL4, RAYL, Intraflagellar transport protein 27 homolog, PutativeGTP-binding protein RAY-like, Rab-like protein 4) - 036897 from USBiological Life Science
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