OBSL1

Gene Symbol OBSL1
Entrez Gene 23363
Alt Symbol -
Species Human
Gene Type protein-coding
Description obscurin-like 1
Other Description obscurin-like protein 1
Swissprots A4KVA4 A4KVA5 S4R3M6 Q96IW3 O75147
Accessions O75147 AB014557 BAA31632 AF035292 AK023854 BAB14704 AK025946 AK299261 BAH12981 BC007201 AAH07201 BC061909 AAH61909 CK904385 DB475523 EF063637 ABO42327 EF063638 ABO42328 F30329 XM_005246424 XP_005246481 XM_005246427 XP_005246484 XM_011510854 XP_011509156 XM_011510855 XP_011509157 XM_011510856 XP_011509158 XM_011510857 XP_011509159 XM_011510858 XP_011509160 XM_011510859 XP_011509161 XM_011510860 XP_011509162 XM_011510861 XP_011509163 XM_011510862 XP_011509164 XM_011510863 XP_011509165 XM_011510864 XP_011509166 XM_011510865 XP_011509167 XM_011510866 XP_011509168 NM_001173408 NP_001166879 NM_001173431 NP_001166902 NM_015311 NP_056126
Function Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Required to localize CUL7 to the Golgi apparatus in neurons. {ECO:0000269|PubMed:21572988, ECO:0000269|PubMed:24793695, ECO:0000269|PubMed:24793696}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Golgi apparatus. Note=Colocalizes with CUL7 at the Golgi apparatus in neurons.
Tissue Specificity Widely expressed, with predominant levels found in the heart. {ECO:0000269|PubMed:17289344}.

OBSL1 (E-16) - sc-241578 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
OBSL1 (E-16): sc-241578. Western blot analysis of OBSL1 expression in rat skeletal muscle tissue extract.

OBSL1 Antibody - NBP1-93625 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: OBSL1 Antibody [NBP1-93625] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

OBSL1 Antibody - NBP2-38299 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: OBSL1 Antibody [NBP2-38299] - Immunofluorescent staining of human cell line U-251 MG shows localization to centrosome.

Anti-OBSL1 antibody produced in rabbit - HPA036404 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-OBSL1: <B>Cat. No. HPA036404</B>: Immunohistochemical staining of human heart muscle shows moderate cytoplasmic positivity.

Anti-OBSL1 polyclonal antibody - DPAB-DC1085 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

OBSL1 (P-20) - sc-241580 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-OBSL1 antibody produced in rabbit - HPA036405 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-OBSL1: <B>Cat. No. HPA036405</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules.

OBSL1 Polyclonal Antibody - CAC08005 from Biomatik

Prices $179.00, $323.00
Sizes 50 μg, 100 μg
Host Rabbit
Clonality Polyclonal

OBSL1, Polyclonal Antibody - MBS7052213 from MyBioSource

Prices $160.00, $235.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

OBSL1, Polyclonal Antibody - MBS7052214 from MyBioSource

Prices $160.00, $235.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

OBSL1, Polyclonal Antibody - MBS7052215 from MyBioSource

Prices $160.00, $235.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

OBSL1, Polyclonal Antibody - MBS7052216 from MyBioSource

Prices $160.00, $235.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

OBSL1 Antibody,Biotin conjugated - CSB-PA016254LD01HU from Cusabio

Host Rabbit
Clonality Polyclonal

OBSL1 Antibody,FITC conjugated - CSB-PA016254LC01HU from Cusabio

Host Rabbit
Clonality Polyclonal

OBSL1 Antibody,HRP conjugated - CSB-PA016254LB01HU from Cusabio

Host Rabbit
Clonality Polyclonal

OBSL1 Antibody - CSB-PA016254LA01HU from Cusabio

Host Rabbit
Clonality Polyclonal

OBSL1 antibody (Biotin) - orb52818 from Biorbyt

Host Rabbit
Clonality Polyclonal

OBSL1 antibody (HRP) - orb52816 from Biorbyt

Host Rabbit
Clonality Polyclonal

OBSL1 antibody - orb52815 from Biorbyt

Host Rabbit
Clonality Polyclonal

OBSL1 antibody (FITC) - orb52817 from Biorbyt

Host Rabbit
Clonality Polyclonal
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