| Gene Symbol |
CD96
|
| Entrez Gene |
10225
|
| Alt Symbol |
TACTILE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD96 molecule
|
| Other Description |
CD96 antigen|T cell activation, increased late expression|T-cell surface protein tactile|cell surface antigen CD96|t cell-activated increased late expression protein
|
| Swissprots |
Q5JPB3 P40200
|
| Accessions |
CCQ43338 EAW79696 EAW79697 EAW79698 P40200 AK290719 BAF83408 AK315237 BAG37664 AL833681 CAI46155 AW341041 BC020749 AAH20749 BC027914 XM_005247063 XP_005247120 XM_006713469 XP_006713532 XM_006713470 XP_006713533 XM_011512324 XP_011510626 XR_241462 XR_241466 XR_924089 XR_924090 NM_005816 NP_005807 NM_198196 NP_937839
|
| Function |
May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells.
|