Gene Symbol | CD96 |
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Entrez Gene | 10225 |
Alt Symbol | TACTILE |
Species | Human |
Gene Type | protein-coding |
Description | CD96 molecule |
Other Description | CD96 antigen|T cell activation, increased late expression|T-cell surface protein tactile|cell surface antigen CD96|t cell-activated increased late expression protein |
Swissprots | Q5JPB3 P40200 |
Accessions | CCQ43338 EAW79696 EAW79697 EAW79698 P40200 AK290719 BAF83408 AK315237 BAG37664 AL833681 CAI46155 AW341041 BC020749 AAH20749 BC027914 XM_005247063 XP_005247120 XM_006713469 XP_006713532 XM_006713470 XP_006713533 XM_011512324 XP_011510626 XR_241462 XR_241466 XR_924089 XR_924090 NM_005816 NP_005807 NM_198196 NP_937839 |
Function | May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells. |
CD96 CRISPR/Cas9 KO Plasmid (h) - sc-407300 from Santa Cruz Biotechnology
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CD96 HDR Plasmid (h) - sc-407300-HDR from Santa Cruz Biotechnology
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CD96 Double Nickase Plasmid (h) - sc-407300-NIC from Santa Cruz Biotechnology
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CD96 Double Nickase Plasmid (h2) - sc-407300-NIC-2 from Santa Cruz Biotechnology
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CD96 CRISPR Activation Plasmid (h) - sc-407300-ACT from Santa Cruz Biotechnology
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CD96 CRISPR Activation Plasmid (h2) - sc-407300-ACT-2 from Santa Cruz Biotechnology
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CD96 Lentiviral Activation Particles (h) - sc-407300-LAC from Santa Cruz Biotechnology
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CD96 Lentiviral Activation Particles (h2) - sc-407300-LAC-2 from Santa Cruz Biotechnology
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CD96 siRNA (h) - sc-45460 from Santa Cruz Biotechnology
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CD96 shRNA Plasmid (h) - sc-45460-SH from Santa Cruz Biotechnology
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CD96 shRNA (h) Lentiviral Particles - sc-45460-V from Santa Cruz Biotechnology
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CD96 RNAi - H00010225-R01 from Novus Biologicals
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CD96 RNAi - H00010225-R02 from Novus Biologicals
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MISSION® esiRNA - EHU145851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5762 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5762 from Sigma-Aldrich
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CD96 siRNA (Human) - CRH6913 from Cohesion Biosciences
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CD96 - MBS8216364 from MyBioSource
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shRNA set against Human CD96 (NM_005816.4) - SHH259501 from Creative biogene
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shRNA set against Human CD96(NM_198196.2) - SHG134767 from Creative biogene
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shRNA set against Human CD96(NM_005816.4) - SHG134821 from Creative biogene
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Human CD96 siRNA - orb267415 from Biorbyt
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CD96 shRNA Plasmid (Human) - CHH6913 from Cohesion Biosciences
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CD96 miRNA 3'UTR clone - MiUTR1H-01917 from Creative biogene
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CD96 miRNA 3'UTR clone - MiUTR1H-01918 from Creative biogene
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