CD96
| Gene Symbol | CD96 |
|---|---|
| Entrez Gene | 10225 |
| Alt Symbol | TACTILE |
| Species | Human |
| Gene Type | protein-coding |
| Description | CD96 molecule |
| Other Description | CD96 antigen|T cell activation, increased late expression|T-cell surface protein tactile|cell surface antigen CD96|t cell-activated increased late expression protein |
| Swissprots | Q5JPB3 P40200 |
| Accessions | CCQ43338 EAW79696 EAW79697 EAW79698 P40200 AK290719 BAF83408 AK315237 BAG37664 AL833681 CAI46155 AW341041 BC020749 AAH20749 BC027914 XM_005247063 XP_005247120 XM_006713469 XP_006713532 XM_006713470 XP_006713533 XM_011512324 XP_011510626 XR_241462 XR_241466 XR_924089 XR_924090 NM_005816 NP_005807 NM_198196 NP_937839 |
| Function | May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells. |
Search more
