| Gene Symbol | GCG |
|---|---|
| Entrez Gene | 2641 |
| Alt Symbol | GLP1, GLP2, GRPP |
| Species | Human |
| Gene Type | protein-coding |
| Description | glucagon |
| Other Description | glicentin-related polypeptide|glucagon-like peptide 1|glucagon-like peptide 2|preproglucagon |
| Swissprots | A6NN65 P01275 Q53TP6 |
| Accessions | AAY24204 CAA24759 CAA27627 EAX11356 EAX11357 EAX11358 P01275 AI818268 BC005278 AAH05278 BG654603 BM272442 BT006813 AAP35459 CB069629 DQ892521 ABM83447 DQ895732 ABM86658 J04040 AAA52567 X05386 X05388 NM_002054 NP_002045 |
| Function | Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain. |
| Top Pathways | Glucagon signaling pathway |