Gene Symbol | GCG |
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Entrez Gene | 2641 |
Alt Symbol | GLP1, GLP2, GRPP |
Species | Human |
Gene Type | protein-coding |
Description | glucagon |
Other Description | glicentin-related polypeptide|glucagon-like peptide 1|glucagon-like peptide 2|preproglucagon |
Swissprots | A6NN65 P01275 Q53TP6 |
Accessions | AAY24204 CAA24759 CAA27627 EAX11356 EAX11357 EAX11358 P01275 AI818268 BC005278 AAH05278 BG654603 BM272442 BT006813 AAP35459 CB069629 DQ892521 ABM83447 DQ895732 ABM86658 J04040 AAA52567 X05386 X05388 NM_002054 NP_002045 |
Function | Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life. |
Subcellular Location | Secreted. |
Tissue Specificity | Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain. |
Top Pathways | Glucagon signaling pathway |
Human GLP1 peptide - ab50245 from Abcam
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Human GLP1 peptide - ab90220 from Abcam
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Human GLP2 peptide - ab42332 from Abcam
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Human GLP2 peptide - ab49543 from Abcam
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Human Glucagon full length protein - ab132833 from Abcam
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Human Glucagon protein fragment - ab109948 from Abcam
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Pig Oxyntomodulin protein fragment - ab73342 from Abcam
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GCG / Glucagon Antibody Blocking Peptide - LS-E8249 from LifeSpan Bioscience
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GCG / Glucagon Antibody Blocking Peptide - LS-E8470 from LifeSpan Bioscience
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GCG / Glucagon Antibody Blocking Peptide - LS-E15464 from LifeSpan Bioscience
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Recombinant Human Glucagon Protein - H00002641-P01 from Novus Biologicals
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Recombinant Human Glucagon Protein - NBP1-72384 from Novus Biologicals
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GCG-Antibody-N-term-Blocking-Peptide - BP6515a from Abgent, a WuXi AppTec company
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Glucagon-Antibody-C-term-Blocking-Peptide - BP6798c from Abgent, a WuXi AppTec company
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Glucagon-19-29-human - SP2518b from Abgent, a WuXi AppTec company
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Glucagon-19-29-human - SP2518a from Abgent, a WuXi AppTec company
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Glucagon-human - SP2841b from Abgent, a WuXi AppTec company
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Glucagon-human - SP2841a from Abgent, a WuXi AppTec company
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Glucagon-Like-Peptide-II-1-34-human - SP2793b from Abgent, a WuXi AppTec company
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Glucagon-Like-Peptide-II-1-34-human - SP2793a from Abgent, a WuXi AppTec company
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GLP-2-human - SP2792b from Abgent, a WuXi AppTec company
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GLP-2-human - SP2792a from Abgent, a WuXi AppTec company
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Glucagon protein - GTX29597 from GeneTex
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Recombinant human Glucagon (OPCA00788) - OPCA00788 from Aviva Systems Biology
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GLP 1 Protein (OPPA01004) - OPPA01004 from Aviva Systems Biology
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