| Gene Symbol |
GCG
|
| Entrez Gene |
2641
|
| Alt Symbol |
GLP1, GLP2, GRPP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glucagon
|
| Other Description |
glicentin-related polypeptide|glucagon-like peptide 1|glucagon-like peptide 2|preproglucagon
|
| Swissprots |
A6NN65 P01275 Q53TP6
|
| Accessions |
AAY24204 CAA24759 CAA27627 EAX11356 EAX11357 EAX11358 P01275 AI818268 BC005278 AAH05278 BG654603 BM272442 BT006813 AAP35459 CB069629 DQ892521 ABM83447 DQ895732 ABM86658 J04040 AAA52567 X05386 X05388 NM_002054 NP_002045
|
| Function |
Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain.
|
| Top Pathways |
Glucagon signaling pathway
|
![Western Blot: Glucagon Overexpression Lysate (Adult Normal) [NBL1-11005] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Glucagon.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5915_Glucagon%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11005-img0002.jpg)