STRADA

Gene Symbol STRADA
Entrez Gene 92335
Alt Symbol LYK5, NY-BR-96, PMSE, STRAD, Stlk
Species Human
Gene Type protein-coding
Description STE20-related kinase adaptor alpha
Other Description STE20-like pseudokinase|STE20-related kinase adapter protein alpha|STRAD alpha|protein kinase LYK5|serologically defined breast cancer antigen NY-BR-96
Swissprots J3KTC9 Q7RTN6 Q7Z4K9 B4DW17 Q8NC31 Q8NCF1 B4DDE3 Q9H272 Q5JPI2
Accessions CAF85943 EAW94283 EAW94284 EAW94285 EAW94286 EAW94287 EAW94288 EAW94289 EAW94290 Q7RTN6 AF308302 AAG48269 AK074771 BAC11197 AK075005 BAC11349 AK128173 AK293160 BAG56704 AK301331 BAG62879 AL832407 CAI46194 AY290821 AAP42280 BC043641 AAH43641 BG339051 BK001542 DAA01797 BQ682133 XM_005257797 XP_005257854 XM_005257798 XP_005257855 XM_005257799 XP_005257856 XM_005257800 XP_005257857 XM_005257801 XP_005257858 XM_005257803 XP_005257860 XM_011525466 XP_011523768 XM_011525467 XP_011523769 XR_243687 XR_243688 NM_001003786 NP_001003786 NM_001003787 NP_001003787 NM_001003788 NP_001003788 NM_001165969 NP_001159441 NM_001165970 NP_001159442 NM_153335 NP_699166
Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. {ECO:0000269|PubMed:12805220, ECO:0000269|PubMed:14517248, ECO:0000269|PubMed:19892943}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12805220, ECO:0000269|PubMed:14517248}. Cytoplasm {ECO:0000269|PubMed:12805220, ECO:0000269|PubMed:14517248}.
Top Pathways AMPK signaling pathway, mTOR signaling pathway

STRAD (D-17) - sc-55051 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

STRAD (M-19) - sc-55052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STRAD (M-19): sc-55052. Western blot analysis of STRAD expression in 293T whole cell lysate.

STRAD (I-13) - sc-34103 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

STRAD (H-83) - sc-99155 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
STRAD (H-83): sc-99155. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

STRAD (N-13) - sc-34102 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STRAD (N-13): sc-34102. Western blot analysis of STRAD expression in Jurkat (A) and A549 (B) whole cell lysates.

STRAD (Y-25) - sc-130882 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
STRAD (Y-25): sc-130882. Western blot analysis of STRAD expression in Jurkat whole cell lysate.

Anti-LYK5 antibody - ab71476 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab71476 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab71476 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-LYK5 antibody - ab64799 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LYK5 antibody (ab64799) at 1/500 dilutionLane 1 : Extracts from HepG2 cellsLane 2 : Extracts from HepG2 cells, plus peptideLysates/proteins at 5 µg per lane.

Anti-LYK5 antibody [EPR15603] - ab192879 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15603
All lanes : Anti-LYK5 antibody [EPR15603] (ab192879) at 1/5000 dilutionLane 1 : 293 cell lysateLane 2 : HepG2 cell lysateLane 3 : HepG2 cell lysateLane 4 : Human fetal brain lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-LYK5 antibody - C-terminal - ab135796 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-LYK5 antibody - C-terminal (ab135796) at 1/100 dilution + Jurkat cell lysate at 12.5 µg

Anti-STRADA / LYK5 Antibody (aa303-346) - LS-C344246 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded M. liver section using STRADA Antibody. Antibody was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Anti-STRADA / LYK5 Antibody (aa300-350) - LS-C19390 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of STRAD inA549 cell lysate in the (A)absence and (B)presence of immunizing peptide using antibody at1 ug/ml.

Anti-STRADA / LYK5 Antibody (aa270-319) - LS-C81343 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-STRADA / LYK5 Antibody (C-Terminus, AP) - LS-C283111 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (C-Terminus, Biotin) - LS-C283112 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (C-Terminus, APC) - LS-C283113 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (C-Terminus, FITC) - LS-C283115 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (C-Terminus, Azide-free, HRP) - LS-C283117 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (N-Terminus, AP) - LS-C283118 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (N-Terminus, Biotin) - LS-C283120 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (C-Terminus, PE) - LS-C283119 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (N-Terminus, APC) - LS-C283121 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (N-Terminus) - LS-C107648 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
STRADA / LYK5 antibody LS-C107648 Western blot of Fetal Spleen lysate.

Anti-STRADA / LYK5 Antibody (N-Terminus, FITC) - LS-C283122 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STRADA / LYK5 Antibody (N-Terminus, Azide-free, HRP) - LS-C283123 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more