STRADA

Gene Symbol STRADA
Entrez Gene 92335
Alt Symbol LYK5, NY-BR-96, PMSE, STRAD, Stlk
Species Human
Gene Type protein-coding
Description STE20-related kinase adaptor alpha
Other Description STE20-like pseudokinase|STE20-related kinase adapter protein alpha|STRAD alpha|protein kinase LYK5|serologically defined breast cancer antigen NY-BR-96
Swissprots J3KTC9 Q7RTN6 Q7Z4K9 B4DW17 Q8NC31 Q8NCF1 B4DDE3 Q9H272 Q5JPI2
Accessions CAF85943 EAW94283 EAW94284 EAW94285 EAW94286 EAW94287 EAW94288 EAW94289 EAW94290 Q7RTN6 AF308302 AAG48269 AK074771 BAC11197 AK075005 BAC11349 AK128173 AK293160 BAG56704 AK301331 BAG62879 AL832407 CAI46194 AY290821 AAP42280 BC043641 AAH43641 BG339051 BK001542 DAA01797 BQ682133 XM_005257797 XP_005257854 XM_005257798 XP_005257855 XM_005257799 XP_005257856 XM_005257800 XP_005257857 XM_005257801 XP_005257858 XM_005257803 XP_005257860 XM_011525466 XP_011523768 XM_011525467 XP_011523769 XR_243687 XR_243688 NM_001003786 NP_001003786 NM_001003787 NP_001003787 NM_001003788 NP_001003788 NM_001165969 NP_001159441 NM_001165970 NP_001159442 NM_153335 NP_699166
Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. {ECO:0000269|PubMed:12805220, ECO:0000269|PubMed:14517248, ECO:0000269|PubMed:19892943}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12805220, ECO:0000269|PubMed:14517248}. Cytoplasm {ECO:0000269|PubMed:12805220, ECO:0000269|PubMed:14517248}.
Top Pathways AMPK signaling pathway, mTOR signaling pathway

STRAD CRISPR/Cas9 KO Plasmid (h) - sc-402311 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STRAD HDR Plasmid (h) - sc-402311-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STRAD Double Nickase Plasmid (h) - sc-402311-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STRAD Double Nickase Plasmid (h2) - sc-402311-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STRAD CRISPR Activation Plasmid (h) - sc-402311-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STRAD CRISPR Activation Plasmid (h2) - sc-402311-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STRAD Lentiviral Activation Particles (h) - sc-402311-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STRAD Lentiviral Activation Particles (h2) - sc-402311-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STRAD siRNA (h) - sc-45241 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STRAD shRNA Plasmid (h) - sc-45241-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STRAD shRNA (h) Lentiviral Particles - sc-45241-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYK5 RNAi - H00092335-R07 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

LYK5 RNAi - H00092335-R08 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

LYK5 RNAi - H00092335-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

LYK5 RNAi - H00092335-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU099541 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK2206 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2209 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2205 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2207 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2208 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2204 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN20764 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09436 from Sigma-Aldrich

Category miRNA
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