S1PR4

Gene Symbol	S1PR4
Entrez Gene	8698
Alt Symbol	EDG6, LPC1, S1P4, SLP4
Species	Human
Gene Type	protein-coding
Description	sphingosine-1-phosphate receptor 4
Other Description	S1P receptor 4|S1P receptor Edg-6|endothelial differentiation G-protein coupled receptor 6|endothelial differentiation, G protein coupled receptor 6|endothelial differentiation, G-protein-coupled receptor 6|endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6|sphingosine 1-phosphate receptor 4|sphingosine 1-phosphate receptor Edg-6
Swissprots	O95977 D6W612
Accessions	AAP84350 EAW69336 EAW69337 O95977 AJ000479 CAA04118 BC014970 AAH14970 FJ200495 ACO54892 NM_003775 NP_003766
Function	Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes. {ECO:0000269|PubMed:10679247, ECO:0000269|PubMed:10753843}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung.
Top Pathways	Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EDG6 full length protein - ab160145 from Abcam Category Protein Source Wheat germ Species Human

S1PR4 / SIP4 / EDG6 Antibody Blocking Peptide - LS-E29212 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

S1PR4 / SIP4 / EDG6 Antibody Blocking Peptide - LS-E29223 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

S1PR4 / SIP4 / EDG6 Antibody Blocking Peptide - LS-E29240 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human S1P4/EDG-6 Protein - H00008698-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human S1P4/EDG-6 Protein - H00008698-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

EDG6 Blocking Peptide - abx063500 from Abbexa Category Peptide Species Human

EDG6 Blocking Peptide - abx063501 from Abbexa Category Peptide Species Human, Mouse, Rat

EDG6 / S1P4 - H00008698-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

EDG6 / S1P4 - H00008698-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

EDG6 / S1P4 - H00008698-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Source in vitro transl. Species Human

EDG6 / S1P4 - H00008698-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Source in vitro transl. Species Human

S1PR4 fusion protein - ag9702 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

EDG6 Blocking Peptide - CBP2306 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

EDG6 Blocking Peptide - CBP2307 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

EDG-6 (S368) Peptide - BS2697P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

EDG-6 Peptide - BS5706P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

S1PR4 Peptide (OEEG01120) - OEEG01120 from Aviva Systems Biology Category Peptide Prices $150.00 Sizes 50 µg Species Human

S1PR4 Peptide (OEEG01163) - OEEG01163 from Aviva Systems Biology Category Peptide Prices $150.00 Sizes 50 µg

S1P4/EDG-6 Recombinant Protein Antigen - NBP2-49317PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

EDG6-Antibody-N-term-Blocking-Peptide - BP6142a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

S1PR4 Peptide, Human - M34GP13740H from Creative Peptides Category Peptide Source Synthetic. Species Human

Sphingosine 1-phosphate receptor 4 (S1PR4), Recombinant Protein - MBS1194777 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Sphingosine 1-phosphate receptor 4 (S1PR4), Recombinant Protein - MBS7056954 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Sphingosine 1-phosphate receptor 4 (S1PR4), Recombinant Protein - MBS7029213 from MyBioSource Category Protein Prices $1,190.00, $2,175.00, $3,385.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Species Human

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