| Gene Symbol |
MEGF11
|
| Entrez Gene |
84465
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
multiple EGF-like-domains 11
|
| Other Description |
multiple EGF-like domains protein 11|multiple epidermal growth factor-like domains protein 11
|
| Swissprots |
Q6UXS5 Q17R86 A6BM72 Q96KG6 Q8ND91
|
| Accessions |
A6BM72 EAW77754 EAW77755 EAW77756 EAW77757 AB058677 BAB47410 AB300051 BAF64841 AK090663 AL834326 CAD38994 AY358226 AAQ88593 BC029999 BC117419 AAI17420 BC126313 AAI26314 XM_011522109 XP_011520411 NM_032445 NP_115821
|
| Function |
May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:17498693}; Single-pass type I membrane protein {ECO:0000269|PubMed:17498693}. Basolateral cell membrane {ECO:0000269|PubMed:17498693}; Single- pass type I membrane protein {ECO:0000269|PubMed:17498693}. Note=Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10.
|