MEGF11

Gene Symbol MEGF11
Entrez Gene 84465
Alt Symbol -
Species Human
Gene Type protein-coding
Description multiple EGF-like-domains 11
Other Description multiple EGF-like domains protein 11|multiple epidermal growth factor-like domains protein 11
Swissprots Q6UXS5 Q17R86 A6BM72 Q96KG6 Q8ND91
Accessions A6BM72 EAW77754 EAW77755 EAW77756 EAW77757 AB058677 BAB47410 AB300051 BAF64841 AK090663 AL834326 CAD38994 AY358226 AAQ88593 BC029999 BC117419 AAI17420 BC126313 AAI26314 XM_011522109 XP_011520411 NM_032445 NP_115821
Function May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17498693}; Single-pass type I membrane protein {ECO:0000269|PubMed:17498693}. Basolateral cell membrane {ECO:0000269|PubMed:17498693}; Single- pass type I membrane protein {ECO:0000269|PubMed:17498693}. Note=Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10.

Mouse MEGF11 ORF clone (NM_032445.2) - CDCL131885 from Creative biogene

Species Human

Human MEGF11 cDNA Clone(NM_032445.2) - CDFG006123 from Creative biogene

Species Human
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