Gene Symbol | TAS2R3 |
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Entrez Gene | 50831 |
Alt Symbol | T2R3 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 3 |
Other Description | candidate taste receptor T2R3|taste receptor type 2 member 3 |
Swissprots | Q645W2 Q75MV6 Q9NYW6 A4D1U2 |
Accessions | AAF43903 AAS02038 AAU21157 BAD97907 BAD97908 BAD97909 CAI53519 CAK32490 EAL24017 EAW83982 Q9NYW6 BC069337 AAH69337 BC095523 AAH95523 NM_016943 NP_058639 |
Function | Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. {ECO:0000269|PubMed:10761934, ECO:0000269|PubMed:10761935}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells. {ECO:0000269|PubMed:10761934}. |
Top Pathways | Taste transduction |
T2R3 (E-12) - sc-398489 from Santa Cruz Biotechnology
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T2R3 (E-13) - sc-163425 from Santa Cruz Biotechnology
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T2R3 (T-14) - sc-163427 from Santa Cruz Biotechnology
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Anti-TAS2R3 antibody - C-terminal - ab138853 from Abcam
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Anti-TAS2R3 Antibody (aa287-313, AP) - LS-C217868 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa287-313, APC) - LS-C217869 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa287-313, FITC) - LS-C217871 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa140-189) - LS-C120962 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa287-313) - LS-C157139 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa287-313, Biotin) - LS-C217870 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa287-313, Azide-free, HRP) - LS-C217872 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa287-313) - LS-C325582 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa287-313, PE) - LS-C217873 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa129-178) - LS-C170518 from LifeSpan Bioscience
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Anti-TAS2R3 Antibody (aa212-261) - LS-C170519 from LifeSpan Bioscience
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TAS2R3 Antibody - NBP1-71309 from Novus Biologicals
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ANTI-TAS2R3(C-TERMINAL) antibody produced in rabbit - SAB1305243 from Sigma-Aldrich
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Anti-TAS2R3 antibody produced in rabbit - SAB4502082 from Sigma-Aldrich
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TAS2R3 Antibody - middle region (ARP68621_P050) - ARP68621_P050 from Aviva Systems Biology
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TAS2R3 Antibody - C-terminal region (ARP68622_P050) - ARP68622_P050 from Aviva Systems Biology
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TAS2R3-Antibody-C-term - AP19081b from Abgent, a WuXi AppTec company
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TAS2R3 Antibody - C-terminal region (OAAB14628) - OAAB14628 from Aviva Systems Biology
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TAS2R3 Antibody (OAAF05229) - OAAF05229 from Aviva Systems Biology
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TAS2R3 antibody - 70R-34365 from Fitzgerald
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TAS2R3 Antibody - abx030765 from Abbexa
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