| Gene Symbol |
TAS2R3
|
| Entrez Gene |
50831
|
| Alt Symbol |
T2R3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
taste receptor, type 2, member 3
|
| Other Description |
candidate taste receptor T2R3|taste receptor type 2 member 3
|
| Swissprots |
Q645W2 Q75MV6 Q9NYW6 A4D1U2
|
| Accessions |
AAF43903 AAS02038 AAU21157 BAD97907 BAD97908 BAD97909 CAI53519 CAK32490 EAL24017 EAW83982 Q9NYW6 BC069337 AAH69337 BC095523 AAH95523 NM_016943 NP_058639
|
| Function |
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. {ECO:0000269|PubMed:10761934, ECO:0000269|PubMed:10761935}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells. {ECO:0000269|PubMed:10761934}.
|
| Top Pathways |
Taste transduction
|
![Western Blot: TAS2R3 Overexpression Lysate (Adult Normal) [NBP2-06986] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TAS2R3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1698_TAS2R3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06986-img0001.jpg)