PALLD

Gene Symbol PALLD
Entrez Gene 23022
Alt Symbol CGI-151, CGI151, MYN, PNCA1, SIH002
Species Human
Gene Type protein-coding
Description palladin, cytoskeletal associated protein
Other Description myoneurin|palladin|sarcoma antigen NY-SAR-77
Swissprots Q7Z3W0 B7ZMM5 B5MD56 Q8WX93 Q86WE8 Q9Y2J6 Q9UQF5 Q7L3E0 B3KTG2 Q9Y3E9 Q8N1M2 Q9UGA0
Accessions AAY40987 CCO13786 EAX04799 Q8WX93 AB023209 BAA76836 AF077041 AAD27774 AF151909 AAD34146 AF464873 AAL69964 AI418424 AK000845 AK025843 AK095512 BAG53074 AK096458 BAC04796 AL050093 CAB43265 AW248292 AY211921 AAO65174 BC013867 AAH13867 BC140850 AAI40851 BC144666 AAI44667 BX537391 CAD97633 DA048169 DA211938 DB257974 XM_005262861 XP_005262918 XM_005262866 XP_005262923 XM_011531768 XP_011530070 XM_011531769 XP_011530071 XM_011531770 XP_011530072 XM_011531771 XP_011530073 XM_011531772 XP_011530074 XM_011531773 XP_011530075 XM_011531774 XP_011530076 XM_011531775 XP_011530077 XM_011531776 XP_011530078 NM_001166108 NP_001159580 NM_001166109 NP_001159581 NM_001166110 NP_001159582 NM_016081 NP_057165
Function Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci. {ECO:0000269|PubMed:11598191, ECO:0000269|PubMed:15147863, ECO:0000269|PubMed:17537434}.
Subcellular Location Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell projection, ruffle. Cell projection, lamellipodium. Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to stress fibers and Z lines.
Tissue Specificity Detected in both muscle and non-muscle tissues. High expression in prostate, ovary, colon, and kidney. Not detected in spleen, skeletal muscle, lung and peripheral blood lymphocytes (at protein level). Protein is overexpressed in FA6, HPAF, IMIM-PC2, SUIT-2 and PancTu-II sporadic pancreatic cancer cell lines. {ECO:0000269|PubMed:11598191}.

palladin (G-2) - sc-166563 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
palladin (G-2): sc-166563. Western blot analysis of palladin expression in CCD-1064Sk whole cell lysate.

palladin (H-100) - sc-68900 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
palladin (H-100): sc-68900. Western blot analysis of palladin expression in 3611-RF (A) and CCD-1064Sk (B) whole cell lysates.

palladin (K-17) - sc-324185 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
palladin (K-17): sc-324185. Western blot analysis of palladin expression in mouse brain (A) and human umbilical (B) tissue extracts.

palladin (P-16) - sc-324187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
palladin (P-16): sc-324187. Western blot analysis of palladin expression in Jurkat whole cell lysate (A) and human umbilical tissue extract (B).

Anti-Palladin antibody - ab92288 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Palladin antibody (ab92288) at 0.1 µg/ml + Human Umbillical Cord lysate at 35 µgdeveloped using the ECL technique

Anti-Palladin antibody [EPR9460(B)] - ab154827 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9460(B)
All lanes : Anti-Palladin antibody [EPR9460(B)] (ab154827) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysateLane 3 : PC3 cell lysateLane 4 : Caco-2 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PALLD / Palladin Antibody (aa13-25) - LS-C87297 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PALLD / Palladin Antibody (aa1154-1304) - LS-C131201 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-PALLD / Palladin Antibody (clone 1E6, Biotin) - LS-C143127 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6

Anti-PALLD / Palladin Antibody (clone 1E6, DY650) - LS-C143128 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6

Anti-PALLD / Palladin Antibody (clone 1E6, DY488) - LS-C143129 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6

Anti-PALLD Antibody (clone 1E6, HRP) - LS-C143130 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6

Anti-PALLD / Palladin Antibody (clone 1E6, DY550) - LS-C143131 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6

Anti-PALLD / Palladin Antibody (N-Terminus) - LS-C346035 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PALLD / Palladin Antibody - LS-C335582 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HepG2 cell line, using PNCA1 antibody.

Anti-PALLD / Palladin Antibody (aa1119-1131) - LS-C112693 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
PALLD antibody (0.1 ug/ml) staining of Human Umbilical Cord lysate (35 ug protein/ml in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PALLD / Palladin Antibody (clone 1E6) - LS-C142728 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6
Palladin Antibody (1E6) - Immunofluorescence on a7r5 cells.

Palladin Antibody (1E6) - NBP1-25959 from Novus Biologicals

Prices $129.00, $299.00
Sizes 25 µl, 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6
Western Blot: Palladin Antibody (1E6) [NBP1-25959] - Western blot analysis of HeLa (A), A431 (B), NIH3T3 (C), and PC-12 (D) cell line extracts using Palladin antibody at 1ug/ml.

Palladin Antibody - AF5950 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, 293T human embryonic kidney cell line, PC‑3 human prostate cancer cell line, and Caki‑2 human clear cell carcinoma epithelial cell line. PVDF Membrane was probed with 0.5 µg/mL of Human Palladin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5950) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). Specific bands were detected for Palladin at approximately 95, 115, and 140 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Myoneurin Antibody (1F10) - NBP2-03899 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F10
Western Blot: Myoneurin Antibody (1F10) [NBP2-03899] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Myoneurin (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Myoneurin.

Myoneurin Antibody - NBP1-92157 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Myoneurin Antibody [NBP1-92157] - Immunofluorescent staining of human cell line A-431 shows localization to nucleus.

Palladin Antibody - NBP1-51931 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: Palladin Antibody [NBP1-51931] - Western blot analysis of Palladin in Human Umbillical Cord lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Palladin Antibody - H00023022-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Palladin Antibody - NBP1-20960 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Palladin Antibody (1E6) [DyLight 488] - NBP1-25959G from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6
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