| Gene Symbol |
PANX1
|
| Entrez Gene |
24145
|
| Alt Symbol |
MRS1, PX1, UNQ2529
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pannexin 1
|
| Other Description |
innexin|pannexin-1
|
| Swissprots |
Q96L77 Q96AM9 Q6UW26 Q543A0 O75968 Q96RS5 Q96RD7
|
| Accessions |
AAK91713 AAL06604 CAF86093 EAW66924 EAW66925 EAW66926 Q96RD7 AF398509 AAK91714 AK074897 BAC11276 AK313074 AY359023 AAQ89382 BC016931 AAH16931 CA418094 FM201789 CAR31475 XM_005273863 XP_005273920 XM_011542734 XP_011541036 NM_015368 NP_056183
|
| Function |
Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. {ECO:0000269|PubMed:16908669, ECO:0000269|PubMed:20829356}.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Cell junction, gap junction {ECO:0000269|PubMed:16908669, ECO:0000269|PubMed:17715132}. Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255|PROSITE- ProRule:PRU00351}.
|