PANX1

Gene Symbol PANX1
Entrez Gene 24145
Alt Symbol MRS1, PX1, UNQ2529
Species Human
Gene Type protein-coding
Description pannexin 1
Other Description innexin|pannexin-1
Swissprots Q96L77 Q96AM9 Q6UW26 Q543A0 O75968 Q96RS5 Q96RD7
Accessions AAK91713 AAL06604 CAF86093 EAW66924 EAW66925 EAW66926 Q96RD7 AF398509 AAK91714 AK074897 BAC11276 AK313074 AY359023 AAQ89382 BC016931 AAH16931 CA418094 FM201789 CAR31475 XM_005273863 XP_005273920 XM_011542734 XP_011541036 NM_015368 NP_056183
Function Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. {ECO:0000269|PubMed:16908669, ECO:0000269|PubMed:20829356}.
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Cell junction, gap junction {ECO:0000269|PubMed:16908669, ECO:0000269|PubMed:17715132}. Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255|PROSITE- ProRule:PRU00351}.

Pannexin-1 (C-16) - sc-49693 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Pannexin-1 (K-20) - sc-49695 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pannexin-1 (K-20): sc-49695. Western blot analysis of Pannexin-1 expression in non-transfected 293: sc-110760 (A) and human Pannexin-1 transfected: sc-113361 (B) 293 whole cell lysates.

Anti-Pannexin 1 antibody - ab124131 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Pannexin 1 antibody (ab124131) at 1 µg/ml + Brain (Human) Tissue Lysate - adult normal tissue (ab29466) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Pannexin 1 antibody - ab139715 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of Pannexin 1 in Human ovary tissue with ab139715 at 20 ug/mL.

Anti-Pannexin 1 antibody - ab105902 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Pannexin 1 antibody (ab105902) at 1 µg/ml + Brain (Human) Tissue Lysate - adult normal tissue (ab29466) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Pannexin 1 antibody [EPR5556] - ab124969 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5556
All lanes : Anti-Pannexin 1 antibody [EPR5556] (ab124969) at 1/1000 dilutionLane 1 : Human fetal brain cell lysatesLane 2 : SH-SY5Y cell lysatesLane 3 : Caco2 cell lysatesLane 4 : NIH OVCAR-3 cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PANX1 / Pannexin 1 Antibody (aa124-152, Biotin) - LS-C238656 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (aa124-152, AP) - LS-C238657 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (aa124-152, APC) - LS-C238658 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (aa124-152, FITC) - LS-C238660 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (aa124-152, Azide-free, HRP) - LS-C248397 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (aa124-152, PE) - LS-C238661 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (aa77-260, Biotin) - LS-C297350 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (aa77-260, FITC) - LS-C302341 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (aa123-152) - LS-C323773 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PANX1 / Pannexin 1 Antibody (Internal, clone EPR5556) - LS-C138631 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5556
Western blot analysis on (A) fetal brain, (B) SH-SY5Y, (C) Caco-2, and (D) NIH: OVCAR-3 cell lysates using anti-Pannexin 1 antibody.

Anti-PANX1 / Pannexin 1 Antibody (aa231-280) - LS-C30513 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PANX1 / Pannexin 1 antibody LS-C30513 was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.

Anti-PANX1 / Pannexin 1 Antibody - LS-C334871 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U2OS cell using PANX1 antibody. Blue: DAPI for nuclear staining.

Anti-PANX1 / Pannexin 1 Antibody (aa77-260) - LS-C295750 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PANX1 / Pannexin 1.

Anti-PANX1 / Pannexin 1 Antibody (aa124-152) - LS-C163354 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PANX1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The PANX1 antibody detected the PANX1 protein (arrow).

Anti-PANX1 / Pannexin 1 Antibody - LS-C343708 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of human Pannexin-1 by PAb to Pannexin-1 (human) (AT124). Cell extracts of HEK 293T mock-transfected (lane 1) or transfected with an expression vector encoding for human Pannexin-1 (lane 2) were run on a SDS-PAGE gel and analyzed by Western blot. After transfer, the nitrocellulose membrane was probed with PAb to Pannexin-1 (human) (AT124) at 1:1000 for 1 hour at room temperature, and then incubated with an anti-rabbit horseradish peroxidase (1:4000).

Anti-PANX1 / Pannexin 1 Antibody (N-Terminus) - LS-C153735 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of PANX1 in human ovary tissue with PANX1 antibody at 20 ug/ml.

Pannexin-1 Antibody - NBP1-59672 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Pannexin-1 Antibody [NBP1-59672] - Sample Tissue: Human 293T Antibody Dilution: 1.0 ug/ml

Pannexin-1 Antibody - NBP1-92241 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Pannexin-1 Antibody (720505) - MAB7097 from Novus Biologicals

Prices $99.00, $259.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 720505
Western blot shows lysates of human brain tissue, mouse brain tissue, and rat brain tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human/Mouse/Rat Pannexin‑1 Monoclonal Antibody (Catalog # MAB7097) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Pannexin‑1 at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
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