Gene Symbol | PANX1 |
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Entrez Gene | 24145 |
Alt Symbol | MRS1, PX1, UNQ2529 |
Species | Human |
Gene Type | protein-coding |
Description | pannexin 1 |
Other Description | innexin|pannexin-1 |
Swissprots | Q96L77 Q96AM9 Q6UW26 Q543A0 O75968 Q96RS5 Q96RD7 |
Accessions | AAK91713 AAL06604 CAF86093 EAW66924 EAW66925 EAW66926 Q96RD7 AF398509 AAK91714 AK074897 BAC11276 AK313074 AY359023 AAQ89382 BC016931 AAH16931 CA418094 FM201789 CAR31475 XM_005273863 XP_005273920 XM_011542734 XP_011541036 NM_015368 NP_056183 |
Function | Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. {ECO:0000269|PubMed:16908669, ECO:0000269|PubMed:20829356}. |
Subcellular Location | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Cell junction, gap junction {ECO:0000269|PubMed:16908669, ECO:0000269|PubMed:17715132}. Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255|PROSITE- ProRule:PRU00351}. |
Pannexin-1 CRISPR/Cas9 KO Plasmid (h) - sc-401635 from Santa Cruz Biotechnology
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Pannexin-1 HDR Plasmid (h) - sc-401635-HDR from Santa Cruz Biotechnology
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Pannexin-1 Double Nickase Plasmid (h) - sc-401635-NIC from Santa Cruz Biotechnology
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Pannexin-1 Double Nickase Plasmid (h2) - sc-401635-NIC-2 from Santa Cruz Biotechnology
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Pannexin-1 CRISPR Activation Plasmid (h) - sc-401635-ACT from Santa Cruz Biotechnology
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Pannexin-1 CRISPR Activation Plasmid (h2) - sc-401635-ACT-2 from Santa Cruz Biotechnology
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Pannexin-1 Lentiviral Activation Particles (h) - sc-401635-LAC from Santa Cruz Biotechnology
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Pannexin-1 Lentiviral Activation Particles (h2) - sc-401635-LAC-2 from Santa Cruz Biotechnology
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Pannexin-1 siRNA (h) - sc-61287 from Santa Cruz Biotechnology
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Pannexin-1 shRNA Plasmid (h) - sc-61287-SH from Santa Cruz Biotechnology
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Pannexin-1 shRNA (h) Lentiviral Particles - sc-61287-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU042141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16307 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16307 from Sigma-Aldrich
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PANX1 siRNA (Human) - CRH8473 from Cohesion Biosciences
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shRNA set against Human PANX1(NM_015368.3) - SHR086988 from Creative biogene
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Human PANX1 siRNA - orb268975 from Biorbyt
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PANX1 shRNA Plasmid (Human) - CHH8473 from Cohesion Biosciences
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PANX1 miRNA 3'UTR clone - MiUTR1H-07490 from Creative biogene
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