URI1

Gene Symbol	URI1
Entrez Gene	8725
Alt Symbol	C19orf2, NNX3, PPP1R19, RMP, URI
Species	Human
Gene Type	protein-coding
Description	URI1, prefoldin-like chaperone
Other Description	RNA polymerase II subunit 5-mediating protein|RPB5-mediating protein|protein phosphatase 1 regulatory subunit 19|protein phosphatase 1, regulatory subunit 19|unconventional prefoldin RPB5 interactor 1
Swissprots	A8K805 Q9UNU3 Q8TC23 H7BY42 O94763
Accessions	O94763 AA678820 AF091095 AAD08679 AK001437 BAG50914 AK226173 AK292170 BAF84859 AK314313 AW003989 AW954529 BC014933 AAH14933 BC026184 AAH26184 BC067259 AAH67259 BG742069 DB461036 HQ234306 XM_005259362 XP_005259419 XM_005259363 XP_005259420 XM_011527435 XP_011525737 NM_001252641 NP_001239570 NM_003796 NP_003787 NR_045557 NM_134447
Function	Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.
Subcellular Location	Nucleus. Cytoplasm. Mitochondrion. Cell projection, dendrite {ECO:0000250}. Note=Colocalizes with PFDN2, PFDN4, PPP1CC, RPS6KB1 and STAP1 at mitochondrion.
Tissue Specificity	Ubiquitous. Expressed in ovarian cancers (at protein level). Expressed strongly in skeletal muscle. Expressed weakly in brain, heart, pancreas and in prostate epithelial cells. {ECO:0000269|PubMed:21397856, ECO:0000269|PubMed:21730289, ECO:0000269|PubMed:9819440, ECO:0000269|PubMed:9878255}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human C19orf2 full length protein - ab81853 from Abcam Category Protein Prices $235.00 Sizes 10 µg Source E. coli Species Human

Recombinant Human URI Protein - H00008725-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human URI Protein - H00008725-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

URI Peptide - P0739 from Novus Biologicals Category Peptide Species Human

RMP-URI-Antibody-C-term-Blocking-peptide - BP1960b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

URI1 peptide - orb218179 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

C19orf2 Blocking Peptide - 33R-6699 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

URI1 Blocking Peptide - abx063510 from Abbexa Category Peptide Species Human, Mouse, Rat

RMP - H00008725-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RMP - H00008725-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RMP - H00008725-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RMP - H00008725-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RMP fusion protein - Ag1789 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human C19ORF2 - C19ORF2-27164TH from Creative Biomart Category Protein Source E. coli

Recombinant Human URI1 - URI1-648H from Creative Biomart Category Protein Source Mammalian Cells Species Human

URI1 Blocking Peptide - CBP2316 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

PPP1R19 Peptide - BS5913P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Unconventional prefoldin RPB5 interactor 1(URI1) - CSB-YP529740HU CSB-EP529740HU CSB-BP529740HU CSB-MP529740HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RMP Protein - abx164974 from Abbexa Category Protein Species Human

RMP (transcript variant 1) - TP317842 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

URI1 Peptide, Human - M34GP17132H from Creative Peptides Category Peptide Source Synthetic. Species Human

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