FGFBP1

Gene Symbol	FGFBP1
Entrez Gene	9982
Alt Symbol	FGF-BP, FGF-BP1, FGFBP, FGFBP-1, HBP17
Species	Human
Gene Type	protein-coding
Description	fibroblast growth factor binding protein 1
Other Description	17 kDa HBGF-binding protein\|17 kDa heparin-binding growth factor-binding protein\|FGF-binding protein 1\|fibroblast growth factor-binding protein 1\|heparin-binding growth factor binding protein
Swissprots	A8K5J2 Q14512
Accessions	AAD39216 EAW92748 Q14512 AK291307 BAF83996 AW959908 BC003628 AAH03628 BC008910 AAH08910 BC018852 BQ435589 BX434467 M60047 AAA58636 NM_005130 NP_005121
Function	Acts as a carrier protein that release fibroblast- binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. {ECO:0000269\|PubMed:11509569, ECO:0000269\|PubMed:15806171, ECO:0000269\|PubMed:1885605, ECO:0000269\|PubMed:9334727}.
Subcellular Location	Secreted, extracellular space. Cell membrane; Peripheral membrane protein. Note=Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas.
Tissue Specificity	Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo- epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas. {ECO:0000269\|PubMed:11148217, ECO:0000269\|PubMed:15806171, ECO:0000269\|PubMed:1885605}.

FGF-BP (Y-16) - sc-68177 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FGF-BP (Y-16): sc-68177. Western blot analysis of FGF-BP expression in AMJ2-C11 (A) and AMJ2-C8 (B) whole cell lysates and mouse embryo tissue extract (C).

FGF-BP (FL-234) - sc-292235 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

FGF-BP (K-15) - sc-68172 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FGF-BP (T-18) - sc-68176 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FGF-BP (4912Z) - sc-73991 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

Anti-FGFBP1 antibody - ab67931 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-FGFBP1 antibody (ab67931) at 1/500 dilutionLane 1 : FGFBP1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

Anti-FGFBP1 antibody [MM0293-5K23] - ab89553 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	MM0293-5K23

Anti-HBP17 / FGFBP1 Antibody - LS-C36358 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-HBP17 / FGFBP1 Antibody (Biotin) - LS-C36359 from LifeSpan Bioscience

Prices	$650.00
Sizes	50 µg
Host	Goat
Clonality	Polyclonal

Anti-HBP17 / FGFBP1 Antibody - LS-C307533 from LifeSpan Bioscience

Prices	$455.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-HBP17 / FGFBP1 Antibody (aa21-238) - LS-C150296 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

FGF-BP in Rat Thymus. FG F-BP was detected in perfusion fixed frozen sections of rat thymus using Rat FGF-BP Antigen Affinity-purified Polyclonal Antibody at 5 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of lymphocytes.

Anti-HBP17 / FGFBP1 Antibody (aa24-234, clone 5F11) - LS-C340466 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	5F11

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGFBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGFBP1 (1:2000).

Anti-HBP17 / FGFBP1 Antibody (aa24-234, clone 2B6) - LS-C340665 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2B6

IHC of paraffin-embedded Human prostate tissue using anti-FGFBP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)(1:150).

FGF-BP Antibody - AF1593 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat
Clonality	Polyclonal

FGF-BP Antibody - NBP1-83904 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: FGF-BP Antibody [NBP1-83904] - Analysis in human cell line A-431.

FGF-BP Antibody - H00009982-B02P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: FGF-BP Antibody [H00009982-B02P] - Analysis of FGFBP1 expression in human ovarian cancer.

FGF-BP Antibody - H00009982-B01P from Novus Biologicals

Prices	$349.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: FGF-BP Antibody [H00009982-B01P] - analysis of FGFBP1 expression in transfected 293T cell line by FGFBP1 MaxPab polyclonal antibody. Lane 1: FGFBP1 transfected lysate (25.85 KDa). Lane 2: Non-transfected lysate.

FGF-BP Antibody (MM0293-5K23) - NBP2-12307 from Novus Biologicals

Prices	$349.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	MM0293-5K23

FGF-BP Antibody [Biotin] - BAF1593 from Novus Biologicals

Prices	$390.00
Sizes	50 µg
Host	Goat
Clonality	Polyclonal

FGFBP1 Polyclonal Antibody - bs-1768R from Bioss

Prices	$279.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin embedded mouse intestine labeled with Anti-FGFBP1 Polyclonal Antibody (bs-1768R), Unconjugated 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-FGFBP1 antibody produced in rabbit - HPA004332 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-FGFBP1: <B>Cat. No. HPA004332</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human esophagus tissue showing cytoplasmic and/or membranous staining of surface epithelial cells.

Anti-FGFBP1 antibody produced in mouse - SAB1406907 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-FGFBP1: <B>Cat. No. SAB1406907</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~25.9 kDa using FGFBP1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-FGFBP1 antibody produced in mouse - SAB1410049 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-FGFBP1: <B>Cat. No. SAB1410049</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~26.3 kDa using human ovary cancer lysate.

FGF-BP antibody [5K23] - GTX52746 from GeneTex

Prices	$319.00
Sizes	100 μg
Host	Mouse
Clonality	Monoclonal
Clone	5K23

Human FGF-BP Antibody - MAB1593 from R&D Systems

Prices	$99.00, $339.00
Sizes	25 µg, 500 µg
Host	Mouse
Clone	196519

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